Compile Data Set for Download or QSAR
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Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50031131
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307877((S)-1-((R)-2-amino-3-phenylpropanoyl)-N-(4-carbami...)
Affinity DataKi:  4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307875((S)-1-((R)-2-amino-4,4-dimethylpentanoyl)-N-(4-car...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307874((S)-1-((R)-2-amino-4-methylpentanoyl)-N-(4-carbami...)
Affinity DataKi:  20nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307876((S)-1-((R)-2-amino-2-cyclohexylacetyl)-N-(4-carbam...)
Affinity DataKi:  23nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307872((S)-1-((R)-2-amino-3-methylbutanoyl)-N-(4-carbamim...)
Affinity DataKi:  70nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307857((S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(3-chl...)
Affinity DataKi:  100nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307856((S)-1-((R)-2-amino-2-cyclohexylacetyl)-N-(3-chloro...)
Affinity DataKi:  150nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307873((S)-1-((R)-2-amino-3,3-dimethylbutanoyl)-N-(4-carb...)
Affinity DataKi:  150nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307858((S)-1-((R)-2-amino-3-phenylpropanoyl)-N-(3-chlorob...)
Affinity DataKi:  180nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  180nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307854((S)-1-((R)-2-amino-4,4-dimethylpentanoyl)-N-(3-chl...)
Affinity DataKi:  410nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307855((S)-1-((R)-2-amino-2-cyclopentylacetyl)-N-(3-chlor...)
Affinity DataKi:  430nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307853((S)-1-((R)-2-amino-4-methylpentanoyl)-N-(3-chlorob...)
Affinity DataKi:  540nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307869((S)-N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl...)
Affinity DataKi:  750nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307852((S)-1-((R)-2-amino-3,3-dimethylbutanoyl)-N-(3-chlo...)
Affinity DataKi:  920nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307863((S)-N-(4-carbamimidoylbenzyl)-1-(3,3-dimethylbutan...)
Affinity DataKi:  940nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307868((S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropa...)
Affinity DataKi:  1.17E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307867((S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylprop...)
Affinity DataKi:  1.18E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307864((S)-N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl...)
Affinity DataKi:  1.28E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307870((S)-1-((R)-2-aminopropanoyl)-N-(4-carbamimidoylben...)
Affinity DataKi:  1.42E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307865((S)-N-(4-carbamimidoylbenzyl)-1-(2-cyclopentylacet...)
Affinity DataKi:  1.64E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307851((S)-1-((R)-2-amino-3-methylbutanoyl)-N-(3-chlorobe...)
Affinity DataKi:  2.54E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307866((S)-N-(4-carbamimidoylbenzyl)-1-(2-cyclohexylacety...)
Affinity DataKi:  3.61E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307862((S)-N-(4-carbamimidoylbenzyl)-1-(3-methylbutanoyl)...)
Affinity DataKi:  3.81E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307861((S)-1-butyryl-N-(4-carbamimidoylbenzyl)pyrrolidine...)
Affinity DataKi:  5.70E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307850((S)-1-((R)-2-aminobutanoyl)-N-(3-chlorobenzyl)pyrr...)
Affinity DataKi:  6.81E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307848((S)-1-(2-aminoacetyl)-N-(3-chlorobenzyl)pyrrolidin...)
Affinity DataKi:  8.08E+3nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307846((S)-N-(3-chlorobenzyl)-1-(3-cyclohexylpropanoyl)py...)
Affinity DataKi:  2.97E+4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307849((S)-1-((R)-2-aminopropanoyl)-N-(3-chlorobenzyl)pyr...)
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307844((S)-N-(3-chlorobenzyl)-1-(2-cyclohexylacetyl)pyrro...)
Affinity DataKi:  3.45E+4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307860((S)-N-(4-carbamimidoylbenzyl)-1-propionylpyrrolidi...)
Affinity DataKi:  3.90E+4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307859((S)-1-acetyl-N-(4-carbamimidoylbenzyl)pyrrolidine-...)
Affinity DataKi:  5.61E+4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307843((S)-N-(3-chlorobenzyl)-1-(2-cyclopentylacetyl)pyrr...)
Affinity DataKi:  7.24E+4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307845((S)-N-(3-chlorobenzyl)-1-(3-cyclopentylpropanoyl)p...)
Affinity DataKi:  9.29E+4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307847((S)-N-(3-chlorobenzyl)-1-(3-phenylpropanoyl)pyrrol...)
Affinity DataKi:  9.43E+4nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307842((S)-N-(3-chlorobenzyl)-1-(4-methylpentanoyl)pyrrol...)
Affinity DataKi:  1.09E+5nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307840((S)-N-(3-chlorobenzyl)-1-(3-methylbutanoyl)pyrroli...)
Affinity DataKi:  1.55E+5nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307839((S)-1-butyryl-N-(3-chlorobenzyl)pyrrolidine-2-carb...)
Affinity DataKi:  3.22E+5nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307838((S)-N-(3-chlorobenzyl)-1-propionylpyrrolidine-2-ca...)
Affinity DataKi:  4.44E+5nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307841((S)-N-(3-chlorobenzyl)-1-(3,3-dimethylbutanoyl)pyr...)
Affinity DataKi:  4.84E+5nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307837((S)-N-(3-chlorobenzyl)-1-acetylpyrrolidine-2-carbo...)
Affinity DataKi:  1.46E+6nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed