Compile Data Set for Download or QSAR
Report error Found 133 Enz. Inhib. hit(s) with all data for entry = 50031438
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313283BDBM50313283(1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataKi:  0.810nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313283BDBM50313283(1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313272BDBM50313272(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 4.10nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313264BDBM50313264(N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 6.90nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313280BDBM50313280(N-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313250BDBM50313250(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1,2...)
Affinity DataIC50: 11.1nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313259BDBM50313259(N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 11.8nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313248BDBM50313248(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313265BDBM50313265(1-benzyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-y...)
Affinity DataIC50: 14.3nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313279BDBM50313279(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 20.9nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313280BDBM50313280(N-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313284BDBM50313284(CHEMBL1822892 | YM-35992 | CHEMBL1080884 | (S)-2-(...)
Affinity DataKi:  21nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313255BDBM50313255(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1-(...)
Affinity DataIC50: 22.9nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313251BDBM50313251(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1-e...)
Affinity DataIC50: 25.8nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313278BDBM50313278(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313277BDBM50313277(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313278BDBM50313278(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313260BDBM50313260(N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 35.9nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313275BDBM50313275(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313275BDBM50313275(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313248BDBM50313248(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 46.2nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313264BDBM50313264(N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 53.6nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313248BDBM50313248(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 54nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313259BDBM50313259(N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313276BDBM50313276(N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313281BDBM50313281(N-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 61nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313281BDBM50313281(N-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 61nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313248BDBM50313248(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 61.7nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313280BDBM50313280(N-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 63nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313268BDBM50313268(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313271BDBM50313271(N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 67.1nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313260BDBM50313260(N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 75nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313279BDBM50313279(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 76nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313282BDBM50313282(N-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 76nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313261BDBM50313261(N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 76nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313258BDBM50313258(N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 77nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313255BDBM50313255(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1-(...)
Affinity DataIC50: 80.2nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313284BDBM50313284(CHEMBL1822892 | YM-35992 | CHEMBL1080884 | (S)-2-(...)
Affinity DataKi:  86nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313275BDBM50313275(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataIC50: 87nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313250BDBM50313250(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1,2...)
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313249BDBM50313249(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-2-m...)
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313251BDBM50313251(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1-e...)
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313263BDBM50313263(N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313278BDBM50313278(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 93nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313252BDBM50313252(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-2-m...)
Affinity DataIC50: 93nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313269BDBM50313269(N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 94nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313279BDBM50313279(N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-...)
Affinity DataIC50: 104nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313254BDBM50313254(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-2-m...)
Affinity DataIC50: 110nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313253BDBM50313253(N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1-i...)
Affinity DataIC50: 110nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Green Cross

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313267BDBM50313267(N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)...)
Affinity DataIC50: 117nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
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