Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 50031512
LigandChemical structure of BindingDB Monomer ID 50314557BDBM50314557((4-(3-(4-(3-nitrophenyl)pyridazino[4,5-b]indolizin...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314558BDBM50314558((4-(3-(4-phenylpyridazino[4,5-b]indolizin-1-ylamin...)
Affinity DataKi:  41nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314583BDBM50314583((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  77nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314557BDBM50314557((4-(3-(4-(3-nitrophenyl)pyridazino[4,5-b]indolizin...)
Affinity DataKi:  147nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314564BDBM50314564(4-(3-nitrophenyl)-N-(3-(4-(pyrimidin-2-yl)piperazi...)
Affinity DataKi:  210nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314581BDBM50314581((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  222nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314578BDBM50314578((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  238nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314571BDBM50314571((4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizi...)
Affinity DataKi:  241nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314557BDBM50314557((4-(3-(4-(3-nitrophenyl)pyridazino[4,5-b]indolizin...)
Affinity DataIC50: 389nMAssay Description:Inhibition of PDE4B3 expressed in CHO cells assessed as isoproterenol-induced [125I]cAMP accumulation after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314570BDBM50314570((4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizi...)
Affinity DataKi:  413nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314577BDBM50314577((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  432nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314580BDBM50314580((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  977nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314575BDBM50314575((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314563BDBM50314563(3-(1-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propylam...)
Affinity DataKi:  1.03E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314560BDBM50314560(4-(3-bromophenyl)-N-(3-(4-(pyrimidin-2-yl)piperazi...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314565BDBM50314565(1-(4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indoli...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314561BDBM50314561(4-(3-chlorophenyl)-N-(3-(4-(pyrimidin-2-yl)piperaz...)
Affinity DataKi:  2.01E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314564BDBM50314564(4-(3-nitrophenyl)-N-(3-(4-(pyrimidin-2-yl)piperazi...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314556BDBM50314556(4-phenyl-N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)pr...)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314562BDBM50314562(4-(3-fluorophenyl)-N-(3-(4-(pyrimidin-2-yl)piperaz...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314568BDBM50314568((4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizi...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314563BDBM50314563(3-(1-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propylam...)
Affinity DataKi:  3.35E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314559BDBM50314559(N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propyl)-4-m...)
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314574BDBM50314574((4-(3-(7-(3-fluorophenyl)-1,2-dimethyl-1H-pyrrolo[...)
Affinity DataKi:  4.40E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314583BDBM50314583((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  4.44E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314582BDBM50314582((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  4.44E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314566BDBM50314566(1-(4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indoli...)
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314557BDBM50314557((4-(3-(4-(3-nitrophenyl)pyridazino[4,5-b]indolizin...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of PDE4D4 expressed in CHO cells assessed as isoproterenol-induced [125I]cAMP accumulation after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314579BDBM50314579((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  5.08E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314569BDBM50314569((4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizi...)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314573BDBM50314573((4-(3-(7-(3-chlorophenyl)-1,2-dimethyl-1H-pyrrolo[...)
Affinity DataKi:  5.50E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314558BDBM50314558((4-(3-(4-phenylpyridazino[4,5-b]indolizin-1-ylamin...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of PDE4B3 expressed in CHO cells assessed as isoproterenol-induced [125I]cAMP accumulation after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314558BDBM50314558((4-(3-(4-phenylpyridazino[4,5-b]indolizin-1-ylamin...)
Affinity DataKi:  8.37E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314578BDBM50314578((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  1.15E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314581BDBM50314581((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  1.27E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314556BDBM50314556(4-phenyl-N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)pr...)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of PDE4B3 expressed in CHO cells assessed as isoproterenol-induced [125I]cAMP accumulation after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314567BDBM50314567(cyclopentyl(4-(3-(4-(3-fluorophenyl)pyridazino[4,5...)
Affinity DataKi:  1.40E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314561BDBM50314561(4-(3-chlorophenyl)-N-(3-(4-(pyrimidin-2-yl)piperaz...)
Affinity DataKi:  1.42E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314577BDBM50314577((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  1.53E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314560BDBM50314560(4-(3-bromophenyl)-N-(3-(4-(pyrimidin-2-yl)piperazi...)
Affinity DataKi:  1.75E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314571BDBM50314571((4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizi...)
Affinity DataKi:  1.80E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314570BDBM50314570((4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizi...)
Affinity DataKi:  1.90E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314568BDBM50314568((4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizi...)
Affinity DataKi:  2.22E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314572BDBM50314572((4-(3-(1,2-dimethyl-7-phenyl-1H-pyrrolo[3,2-d]pyri...)
Affinity DataKi:  2.62E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314580BDBM50314580((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  4.86E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314582BDBM50314582((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  5.12E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314576BDBM50314576((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...)
Affinity DataKi:  5.22E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314559BDBM50314559(N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propyl)-4-m...)
Affinity DataKi:  5.44E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314556BDBM50314556(4-phenyl-N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)pr...)
Affinity DataKi:  5.90E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50314567BDBM50314567(cyclopentyl(4-(3-(4-(3-fluorophenyl)pyridazino[4,5...)
Affinity DataKi:  6.10E+4nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
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