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Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50031631
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316422((5R,11aR)-5-(2-Bromophenyl)-2-ethyl-5,6,11,11a-tet...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316440((6R,12aS)-2-Benzyl-6-(2-bromophenyl)-2,3,6,7,12,12...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316436((6R,12aS)-6-(2-Bromophenyl)-2-ethyl-2,3,6,7,12,12a...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316438((6R,12aS)-6-(2-Bromophenyl)-2-butyl-2,3,6,7,12,12a...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316432((6R,12aS)-6-(2-Bromophenyl)-2-methyl-2,3,6,7,12,12...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316429((6R,12aR)-6-(2-Bromophenyl)-2-methyl-2,3,6,7,12,12...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316437((6R,12aR)-6-(2-Bromophenyl)-2-butyl-2,3,6,7,12,12a...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316422((5R,11aR)-5-(2-Bromophenyl)-2-ethyl-5,6,11,11a-tet...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316433((6R,12aR)-6-(2-Bromophenyl)-2-ethyl-2,3,6,7,12,12a...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316423((5S,11aR)-5-(2-Bromophenyl)-2-ethyl-5,6,11,11a-tet...)
Affinity DataIC50:  640nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316431((6S,12aS)-6-(2-Bromophenyl)-2-methyl-2,3,6,7,12,12...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316421((1R,3S)Methyl 1-(2-bromophenyl)-2,3,4,9-tetrahydro...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316439((6R,12aR)-2-Benzyl-6-(2-bromophenyl)-2,3,6,7,12,12...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316423((5S,11aR)-5-(2-Bromophenyl)-2-ethyl-5,6,11,11a-tet...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316420((1R,3R)Methyl 1-(2-bromophenyl)-2,3,4,9-tetrahydro...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316427((5R-11aS)-5-(2-Bromophenyl)-2-ethyl-1-oxo-5,6,11,1...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316428(CHEMBL1097216 | Methyl(1R,3R)-1-(2-bromophenyl)-2-...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316435((6S,12aS)-6-(2-Bromophenyl)-2-ethyl-2,3,6,7,12,12a...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316434((6S,12aR)-6-(2-Bromophenyl)-2-ethyl-2,3,6,7,12,12a...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316426((5S,11aR)-5-(2-Bromophenyl)-2-ethyl-1-oxo-5,6,11,1...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50316430((6S,12aR)-6-(2-Bromophenyl)-2-methyl-2,3,6,7,12,12...)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed