Compile Data Set for Download or QSAR
Report error Found 174 Enz. Inhib. hit(s) with all data for entry = 50031542
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315021BDBM50315021((R)-N-(2-(1-(2-(4-(2-chlorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315022BDBM50315022((R)-N-(2-(1-(2-(4-(2-fluorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315023BDBM50315023((R)-N-(2-(1-(2-(4-(2,5-difluorobenzoyl)piperazin-1...)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315020BDBM50315020((R)-N-(2-(1-(2-(4-benzoylpiperazin-1-yl)ethyl)pyrr...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315027BDBM50315027((R)-N-(2-(1-(2-(1-(2-chlorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315023BDBM50315023((R)-N-(2-(1-(2-(4-(2,5-difluorobenzoyl)piperazin-1...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315026BDBM50315026((R)-N-(2-(1-(2-(1-(2,5-difluorobenzoyl)piperidin-4...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315027BDBM50315027((R)-N-(2-(1-(2-(1-(2-chlorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315020BDBM50315020((R)-N-(2-(1-(2-(4-benzoylpiperazin-1-yl)ethyl)pyrr...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315024BDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315021BDBM50315021((R)-N-(2-(1-(2-(4-(2-chlorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315025BDBM50315025((R)-N-(2-(1-(2-(1-(2-fluorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315024BDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315025BDBM50315025((R)-N-(2-(1-(2-(1-(2-fluorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315026BDBM50315026((R)-N-(2-(1-(2-(1-(2,5-difluorobenzoyl)piperidin-4...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315028BDBM50315028(cis-(1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-i...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315022BDBM50315022((R)-N-(2-(1-(2-(4-(2-fluorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315041BDBM50315041((R)-N-(2-(1-(2-(4-(4-methylbenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315039BDBM50315039((R)-N-(2-(1-(2-(4-(2-methylbenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315029BDBM50315029((R)-N-(2-(1-(2-(1-(3-fluorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315040BDBM50315040((R)-N-(2-(1-(2-(4-(3-methylbenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236430BDBM50236430((R)-N-(2-(1-(4-chlorobenzyl)pyrrolidin-3-ylamino)-...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315034BDBM50315034((R)-N-(2-(1-(2-(1-(2-methylbenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 520nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315024BDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: 580nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 610nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315036BDBM50315036((R)-N-(2-(1-(2-(1-(4-methylbenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 620nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315033BDBM50315033((R)-N-(2-oxo-2-(1-(2-(1-(4-(trifluoromethyl)benzoy...)
Affinity DataIC50: 660nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315043BDBM50315043(N-(2-((3R)-1-(2-(4-benzoylpiperazin-1-yl)propyl)py...)
Affinity DataIC50: 710nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315035BDBM50315035((R)-N-(2-(1-(2-(1-(3-methylbenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 750nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236430BDBM50236430((R)-N-(2-(1-(4-chlorobenzyl)pyrrolidin-3-ylamino)-...)
Affinity DataIC50: 980nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315020BDBM50315020((R)-N-(2-(1-(2-(4-benzoylpiperazin-1-yl)ethyl)pyrr...)
Affinity DataIC50: 990nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315036BDBM50315036((R)-N-(2-(1-(2-(1-(4-methylbenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315042BDBM50315042((R)-N-(2-(1-(2-(4-(4-fluorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315021BDBM50315021((R)-N-(2-(1-(2-(4-(2-chlorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 1.12E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315025BDBM50315025((R)-N-(2-(1-(2-(1-(2-fluorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 1.13E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315035BDBM50315035((R)-N-(2-(1-(2-(1-(3-methylbenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 1.18E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315028BDBM50315028(cis-(1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-i...)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315027BDBM50315027((R)-N-(2-(1-(2-(1-(2-chlorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 1.31E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315026BDBM50315026((R)-N-(2-(1-(2-(1-(2,5-difluorobenzoyl)piperidin-4...)
Affinity DataIC50: 1.41E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315038BDBM50315038((R)-N-(2-oxo-2-(1-(2-(1-(4-propylbenzoyl)piperidin...)
Affinity DataIC50: 1.73E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315037BDBM50315037((R)-N-(2-(1-(2-(1-(4-ethylbenzoyl)piperidin-4-yl)e...)
Affinity DataIC50: 1.74E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315044BDBM50315044(N-(2-((3R)-1-(1-(4-benzoylpiperazin-1-yl)propan-2-...)
Affinity DataIC50: 1.86E+3nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315022BDBM50315022((R)-N-(2-(1-(2-(4-(2-fluorobenzoyl)piperazin-1-yl)...)
Affinity DataIC50: 1.88E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315033BDBM50315033((R)-N-(2-oxo-2-(1-(2-(1-(4-(trifluoromethyl)benzoy...)
Affinity DataIC50: 2.21E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239941BDBM50239941((S)-1-(4-(1-(4-(1H-indol-3-yl)piperidin-1-yl)-2-hy...)
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315034BDBM50315034((R)-N-(2-(1-(2-(1-(2-methylbenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 2.88E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315023BDBM50315023((R)-N-(2-(1-(2-(4-(2,5-difluorobenzoyl)piperazin-1...)
Affinity DataIC50: 3.04E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315031BDBM50315031((R)-N-(2-(1-(2-(1-(4-chlorobenzoyl)piperidin-4-yl)...)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
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