Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50031557
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Graz

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 level by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
University Of Graz

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of sheep placental cotyledens COX2 assessed as PGE2 level by EIAMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Graz

Curated by ChEMBL
LigandPNGBDBM50315285(CHEMBL1089840 | aR-6,7-dihydro-6-(10-hydroxyethyl)...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of 5-LOX-mediated LTB4 production in stimulated human neutrophile granulocytes after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Graz

Curated by ChEMBL
LigandPNGBDBM50315286(CHEMBL1088887 | aR-6-(10-iodoethyl)-1,2,3,9,10,11-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of 5-LOX-mediated LTB4 production in stimulated human neutrophile granulocytes after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Graz

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of 5-LOX-mediated LTB4 production in stimulated human neutrophile granulocytes after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
University Of Graz

Curated by ChEMBL
LigandPNGBDBM50315284(CHEMBL1089510 | aR-6,7-Dihydro-6-(10-hydroxyethyl)...)
Affinity DataIC50:  3.21E+4nMAssay Description:Inhibition of sheep placental cotyledens COX2 assessed as PGE2 level by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed