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Report error Found 143 Enz. Inhib. hit(s) with all data for entry = 50031570
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315482(CHEMBL1093897 | N-(3-chlorophenylsulfonyl)-3-(3,3-...)
Affinity DataIC50:  0.100nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315471(3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315493(3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(2,...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315474(CHEMBL1089095 | N-(3-chlorophenylsulfonyl)-3-(1-(2...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315472(3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315476(3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315473(3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315480(3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoind...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315479(3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoind...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315528(3-(3-methyl-1-(naphthalen-2-ylmethyl)-2-oxoindolin...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315498(3-(1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)-N-...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315481(CHEMBL1090222 | N-(3,4-dichlorophenylsulfonyl)-3-(...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315503(CHEMBL1092871 | N-(3,4-dichlorophenylsulfonyl)-3-(...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315521(3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315529(CHEMBL1089454 | N-(3-chlorophenylsulfonyl)-3-(3-me...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315499(CHEMBL1088822 | N-(3,4-difluorophenylsulfonyl)-3-(...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315504(CHEMBL1088848 | N-(3-chlorophenylsulfonyl)-3-(1-(3...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315506(CHEMBL1091146 | N-(4,5-dichlorothiophen-2-ylsulfon...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315492(CHEMBL1092230 | N-(3-chlorophenylsulfonyl)-3-(1-(2...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315500(CHEMBL1088823 | N-(3,4-dichlorophenylsulfonyl)-3-(...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315523(CHEMBL1089161 | N-(3-chlorophenylsulfonyl)-3-(1-(2...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315524(3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315530(CHEMBL1089455 | N-(3,4-dichlorophenylsulfonyl)-3-(...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315527(CHEMBL1090459 | N-(3,4-difluorophenylsulfonyl)-3-(...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315469(3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindoli...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315518(3-(1-(naphthalen-2-ylmethyl)-2,3-dioxoindolin-7-yl...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315501(CHEMBL1088846 | N-(3-chlorophenylsulfonyl)-3-(1-(n...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315494(3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(3,...)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315505(3-(1-(3,4-difluorobenzyl)-2-oxoindolin-7-yl)-N-(2,...)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315531(CHEMBL1093124 | N-(3,4-dichlorophenylsulfonyl)-3-(...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315502(3-(1-(3,4-difluorobenzyl)-2-oxoindolin-7-yl)-N-(3,...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315522(3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315467(CHEMBL1093791 | N-(4-fluorophenylsulfonyl)-3-(3-hy...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315517(CHEMBL1093133 | N-(3,4-dichlorophenylsulfonyl)-3-(...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315475(CHEMBL1091606 | N-(4-chlorophenylsulfonyl)-3-(1-(2...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315495(3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(3,...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315488(CHEMBL1091622 | N-(3,4-dichlorophenylsulfonyl)-3-(...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315487(3-(1-(3,4-difluorobenzyl)-3,3-difluoro-2-oxoindoli...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315496(CHEMBL1088785 | N-(4,5-dichlorothiophen-2-ylsulfon...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315532(3-(1-(3,4-difluorobenzyl)-3-methyl-2-oxoindolin-7-...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315516(CHEMBL1090455 | N-(4-fluorophenylsulfonyl)-3-(1-(n...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315468(CHEMBL1093792 | N-(3,4-difluorophenylsulfonyl)-3-(...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315482(CHEMBL1093897 | N-(3-chlorophenylsulfonyl)-3-(3,3-...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315507(3-(3,3-bis(hydroxymethyl)-1-(naphthalen-2-ylmethyl...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315519(3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315483(3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoind...)
Affinity DataIC50:  2.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315529(CHEMBL1089454 | N-(3-chlorophenylsulfonyl)-3-(3-me...)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315490(3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(4,...)
Affinity DataIC50:  2.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315526(CHEMBL1090458 | N-(4,5-dichlorothiophen-2-ylsulfon...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315521(3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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