Compile Data Set for Download or QSAR
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Found 48 Enz. Inhib. hit(s) with all data for entry = 50031596
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315949((S)-N-(4-aminobutyl)-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315959(CHEMBL1091614 | N-(4-aminobutyl)-N-(2-(4-hydroxycy...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315931((S)-N-ethyl-3-methyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315958(CHEMBL1089655 | N-(4-aminobutyl)-N-(2-(isopropylam...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315917((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315951(CHEMBL1093834 | N-(2-(isopropylamino)pyrimidin-4-y...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315960((S)-N-(4-aminobutyl)-N-(2-(1-methoxypropan-2-ylami...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315938((S)-N-ethyl-2-fluoro-5-methyl-N-(2-(1-phenylethyla...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315937((S)-N-ethyl-4-fluoro-3-methyl-N-(2-(1-phenylethyla...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315922((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315943((S)-N-(2-(1-phenylethylamino)pyrimidin-4-yl)-N-(pi...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315916((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315936((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315934((S)-N,3-diethyl-N-(2-(1-phenylethylamino)pyrimidin...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315920((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315919((S)-N-(3-(methylsulfonyl)propyl)-N-(2-(1-phenyleth...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315929((S)-3-chloro-N-ethyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315933((S)-N-ethyl-2,3-dimethyl-N-(2-(1-phenylethylamino)...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315921((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315932((S)-N-ethyl-3,4-dimethyl-N-(2-(1-phenylethylamino)...)
Affinity DataIC50:  91nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315950((S)-N-(4-hydroxybutyl)-N-(2-(1-phenylethylamino)py...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315935((S)-3-cyclopropyl-N-ethyl-N-(2-(1-phenylethylamino...)
Affinity DataIC50:  104nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315925((S)-N-ethyl-1-methyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50:  154nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315942((S)-N-(2-(1-phenylethylamino)pyrimidin-4-yl)-N-((t...)
Affinity DataIC50:  158nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315918((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  164nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315940((S)-N-(cyclopropylmethyl)-N-(2-(1-phenylethylamino...)
Affinity DataIC50:  165nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315926((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  179nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315923((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315924((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  188nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315927((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50:  193nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315928((S)-2-chloro-N-ethyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50:  267nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315961((S)-N-(4-aminobutyl)-N-(2-(1-hydroxypropan-2-ylami...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315875((S)-N-ethyl-N-(2-(1-phenylethylamino)pyridin-4-yl)...)
Affinity DataIC50:  313nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315930((S)-4-chloro-N-ethyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50:  313nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315954((S)-N-(2-(1-methoxypropan-2-ylamino)pyrimidin-4-yl...)
Affinity DataIC50:  316nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315941((S)-N-(2-methoxyethyl)-N-(2-(1-phenylethylamino)py...)
Affinity DataIC50:  345nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315952(CHEMBL1091228 | N-(2-(4-hydroxycyclohexylamino)pyr...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315953(CHEMBL1091229 | N-(2-(4-aminocyclohexylamino)pyrim...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315939((S)-N-isobutyl-N-(2-(1-phenylethylamino)pyrimidin-...)
Affinity DataIC50:  462nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315956(CHEMBL1091635 | N-(2-(1-methoxybutan-2-ylamino)pyr...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315957(CHEMBL1091636 | N-(2-(cyclopropylamino)pyrimidin-4...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315947((S)-N-(2-(1-phenylethylamino)pyrimidin-4-yl)-N-((1...)
Affinity DataIC50:  673nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315946((S)-4-((N-(2-(1-phenylethylamino)pyrimidin-4-yl)-2...)
Affinity DataIC50:  711nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315866(CHEMBL1091737 | N-(4-fluorobenzyl)-N-(pyridin-4-yl...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315955(CHEMBL1091634 | N-(2-(1-hydroxy-2-methylpropan-2-y...)
Affinity DataIC50:  3.04E+3nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315944(CHEMBL1090231 | N-(2-((S)-1-phenylethylamino)pyrim...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315945(CHEMBL1093580 | N-(2-((S)-1-phenylethylamino)pyrim...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50315948((S)-N-(3-aminopropyl)-N-(2-(1-phenylethylamino)pyr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed