Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50031722
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317931BDBM50317931((2R*,3S*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317932BDBM50317932((2R*,3S*,4R*,6S*)-2-(4-Chlorophenyl)tetrahydro-3,4...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317924BDBM50317924((2R*,4R*,6S*)-2-(4-Chlorophenyl)tetrahydro-4-pheny...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317930BDBM50317930((2R*,3S*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-3,4...)
Affinity DataIC50: 1.11nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317929BDBM50317929((2R*,3S*,4R*,6S*)-6-((Ethylthio)methyl)-2-(4-fluor...)
Affinity DataIC50: 1.28nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317920BDBM50317920((2R*,4R*,6S*)-Tetrahydro-2,4-diphenyl-6-(thiocyana...)
Affinity DataIC50: 1.47nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317928BDBM50317928((2R*,3S*,4R*,6S*)-Tetrahydro-2,3,4-triphenyl-6-(th...)
Affinity DataIC50: 1.55nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317927BDBM50317927((2R*,3S*,4R*,6S*)-6-((Ethylthio)methyl)tetrahydro-...)
Affinity DataIC50: 1.72nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317923BDBM50317923((2R*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio)met...)
Affinity DataIC50: 1.82nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317921BDBM50317921((2S*,4R*,6R*)-2-((Ethylthio)methyl)-6-(4-fluorophe...)
Affinity DataIC50: 2.05nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317919BDBM50317919((2S*,4R*,6R*)-2-((Ethylthio)methyl)tetrahydro-4,6-...)
Affinity DataIC50: 2.07nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317933BDBM50317933((2R*,3S*,4R*,6S*)-2-(4-Bromophenyl)-6-((ethylthio)...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317922BDBM50317922((2R*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-4-pheny...)
Affinity DataIC50: 3.57nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317926BDBM50317926((2R*,4R*,6S*)-2-(4-Bromophenyl)tetrahydro-4-phenyl...)
Affinity DataIC50: 4.01nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317934BDBM50317934((2R*,3S*,4R*,6S*)-2-(4-Bromophenyl)tetrahydro-3,4-...)
Affinity DataIC50: 4.03nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317925BDBM50317925((2R*,4R*,6S*)-2-(4-Bromophenyl)-6-((ethylthio)meth...)
Affinity DataIC50: 5.49nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317918BDBM50317918((2S*,4R*,6S*)-Tetrahydro-2-methyl-4-phenyl-6-(thio...)
Affinity DataIC50: 117nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317917BDBM50317917((2S*,4R*,6S*)-2-((Ethylthio)methyl)tetrahydro-6-me...)
Affinity DataIC50: 175nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317926BDBM50317926((2R*,4R*,6S*)-2-(4-Bromophenyl)tetrahydro-4-phenyl...)
Affinity DataIC50: 209nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317917BDBM50317917((2S*,4R*,6S*)-2-((Ethylthio)methyl)tetrahydro-6-me...)
Affinity DataIC50: 347nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317918BDBM50317918((2S*,4R*,6S*)-Tetrahydro-2-methyl-4-phenyl-6-(thio...)
Affinity DataIC50: 368nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317923BDBM50317923((2R*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio)met...)
Affinity DataIC50: 413nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317922BDBM50317922((2R*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-4-pheny...)
Affinity DataIC50: 488nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22369BDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317925BDBM50317925((2R*,4R*,6S*)-2-(4-Bromophenyl)-6-((ethylthio)meth...)
Affinity DataIC50: 562nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317924BDBM50317924((2R*,4R*,6S*)-2-(4-Chlorophenyl)tetrahydro-4-pheny...)
Affinity DataIC50: 664nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317921BDBM50317921((2S*,4R*,6R*)-2-((Ethylthio)methyl)-6-(4-fluorophe...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317920BDBM50317920((2R*,4R*,6S*)-Tetrahydro-2,4-diphenyl-6-(thiocyana...)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317919BDBM50317919((2S*,4R*,6R*)-2-((Ethylthio)methyl)tetrahydro-4,6-...)
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317931BDBM50317931((2R*,3S*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317934BDBM50317934((2R*,3S*,4R*,6S*)-2-(4-Bromophenyl)tetrahydro-3,4-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317927BDBM50317927((2R*,3S*,4R*,6S*)-6-((Ethylthio)methyl)tetrahydro-...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317933BDBM50317933((2R*,3S*,4R*,6S*)-2-(4-Bromophenyl)-6-((ethylthio)...)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317932BDBM50317932((2R*,3S*,4R*,6S*)-2-(4-Chlorophenyl)tetrahydro-3,4...)
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317930BDBM50317930((2R*,3S*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-3,4...)
Affinity DataIC50: 2.89E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317929BDBM50317929((2R*,3S*,4R*,6S*)-6-((Ethylthio)methyl)-2-(4-fluor...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317928BDBM50317928((2R*,3S*,4R*,6S*)-Tetrahydro-2,3,4-triphenyl-6-(th...)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22369BDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed