Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50031645
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM7977((3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM7974(CHEMBL113208 | (3S,4S)-N-[(1S)-1-{[(1S)-1-carbamoy...)
Affinity DataKi:  0.560nMAssay Description:Inhibition of Plasmodium falciparum recombinant plasmepsin-2 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316597(N-((S)-1-((2S,3S)-3-hydroxy-5-oxo-5-((S)-1-oxo-3-p...)
Affinity DataIC50: 22nMAssay Description:Competitive inhibition of Plasmodium falciparum plasmepsin-2 expressed in Escherichia coli BL21 (DE3) after 30 min by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316596(N-((S)-1-((2S,3S)-5-((R)-1-((S)-1-amino-4-methyl-1...)
Affinity DataIC50: 28nMAssay Description:Competitive inhibition of Plasmodium falciparum plasmepsin-2 expressed in Escherichia coli BL21 (DE3) after 30 min by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316596(N-((S)-1-((2S,3S)-5-((R)-1-((S)-1-amino-4-methyl-1...)
Affinity DataKi:  35.7nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 expressed in Escherichia coli BL21 (DE3) after 40 min by Kitz-Wilson plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316599(N-((S)-1-((2S,3S)-5-((S)-1-((S)-1-amino-4-methyl-1...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human cathepsin D after 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316598(N-((S)-1-((2S,3S)-5-((S)-1-((S)-1-amino-4-methyl-1...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human cathepsin D after 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316597(N-((S)-1-((2S,3S)-3-hydroxy-5-oxo-5-((S)-1-oxo-3-p...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human cathepsin D after 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316596(N-((S)-1-((2S,3S)-5-((R)-1-((S)-1-amino-4-methyl-1...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human cathepsin D after 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM8027((2S)-N-[(2S,3S)-4-{[(1S)-1-carbamoyl-2-[4-(4-methy...)
Affinity DataKi:  121nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316599(N-((S)-1-((2S,3S)-5-((S)-1-((S)-1-amino-4-methyl-1...)
Affinity DataIC50: 141nMAssay Description:Competitive inhibition of Plasmodium falciparum plasmepsin-2 expressed in Escherichia coli BL21 (DE3) after 30 min by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316598(N-((S)-1-((2S,3S)-5-((S)-1-((S)-1-amino-4-methyl-1...)
Affinity DataIC50: 333nMAssay Description:Competitive inhibition of Plasmodium falciparum plasmepsin-2 expressed in Escherichia coli BL21 (DE3) after 30 min by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316598(N-((S)-1-((2S,3S)-5-((S)-1-((S)-1-amino-4-methyl-1...)
Affinity DataKi:  333nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 expressed in Escherichia coli BL21 (DE3) after 40 min by Kitz-Wilson plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50119879(N-{4-[2-(2,6-Dimethyl-phenoxy)-acetylamino]-3-hydr...)
Affinity DataKi:  357nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed