Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 50031883
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  160nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320969(CHEMBL1164353 | Phenyl-1H-pyrazol-3-yl)-1H-indole-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  400nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320992(2-(5-Benzyl-1H-pyrazol-3-yl)-3-[(4-fluorobenzylami...)
Affinity DataIC50:  500nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  540nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320979(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  560nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320978(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320994(2-(5-Benzyl-1H-pyrazol-3-yl)-3-morpholin-4-ylmethy...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  630nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  790nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320991(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  850nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320972(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320977(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320987(2-(5-Benzyl-1H-pyrazol-3-yl)-3-hydroxymethyl-1Hind...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320975(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320974(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320971(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320976(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320980(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320973(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320969(CHEMBL1164353 | Phenyl-1H-pyrazol-3-yl)-1H-indole-...)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320981(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320984(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320983(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  4.36E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320988(2-(5-benzyl-1H-pyrazol-3-yl)-N-methyl-3-((pyridin-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320978(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320970(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  5.75E+3nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320969(CHEMBL1164353 | Phenyl-1H-pyrazol-3-yl)-1H-indole-...)
Affinity DataIC50:  6.76E+3nMAssay Description:Inhibition of GST-tagged full length GSK3-beta assessed as inhibition of ATP consumption after 60 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320967(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  7.08E+3nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320968(2-(4-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  9.33E+3nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320982(2-(5-Phenyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320969(CHEMBL1164353 | Phenyl-1H-pyrazol-3-yl)-1H-indole-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320989(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320990(3-[(4-Methoxy-benzylamino)-methyl]-2-(4-phenyl-1Hp...)
Affinity DataIC50:  2.04E+4nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320978(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of GST-tagged full length CDK2/Cyclin E after 40 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320985(2-(5-Benzyl-1H-pyrazol-3-yl)-3-[(4-hydroxybutylami...)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320979(2-(5-Benzyl-1H-pyrazol-3-yl)-1H-indole-6-carboxyli...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged recombinant INSR catalytic domain expressed in baculovirus-infected Sf21 cells after 80 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320993(3-Hydroxymethyl-2-(4-phenyl-1H-pyrazol-3-yl)-1Hind...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed Pharma

Curated by ChEMBL
LigandPNGBDBM50320986(3-[(3-Hydroxy-propylamino)-methyl]-2-(4-phenyl-1Hp...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged full length recombinant ITK after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed