Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50032289
TargetEstrogen receptor(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50326712(2(R)-[4(S)-carboxy-4-[4-[N-(2-hydroxymethyl-4-oxo-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ERalpha expressed in human tumor cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50326712(2(R)-[4(S)-carboxy-4-[4-[N-(2-hydroxymethyl-4-oxo-...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of thymine synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of thymine synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50326711(1,3-propanediphosphonic acid | PROPANE-1,3-DIYLBIS...)
Affinity DataKi:  260nMAssay Description:Inhibition of human Thymidylate synthase by uncompetitive bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataKi:  380nMAssay Description:Inhibition of GARFTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Institute of Theoretical Studies Ggmbh

Curated by ChEMBL
LigandPNGBDBM50326711(1,3-propanediphosphonic acid | PROPANE-1,3-DIYLBIS...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human Thymidylate synthase by noncompetitive bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)