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Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 50031847
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320443(4-(4-(4-(4-(2,3-dimethylphenyl)piperazine-1-carbon...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320424(4-(4-(4-(3,5-dimethylpiperazine-1-carbonyl)piperid...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320435(4-(4-(4-(4-(4-fluorophenyl)piperazine-1-carbonyl)p...)
Affinity DataIC50:  6nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320423(4-(4-(4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320439(CHEMBL1084298 | N-hydroxy-4-(4-(4-(4-(pyrimidin-2-...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320436(4-(4-(4-(4-(4-acetylphenyl)piperazine-1-carbonyl)p...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320433(4-(4-(4-(4-(2-fluorophenyl)piperazine-1-carbonyl)p...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320422(CHEMBL1082324 | N-hydroxy-4-(4-(4-(1,2,3,4-tetrahy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320438(CHEMBL1084024 | N-hydroxy-4-(4-(4-(4-(pyridin-2-yl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320437(4-(4-(4-(4-(2,4-dimethylphenyl)piperazine-1-carbon...)
Affinity DataIC50:  12nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320434(CHEMBL1083584 | N-hydroxy-4-(4-(4-(4-(2-methoxyphe...)
Affinity DataIC50:  18nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320426(CHEMBL1083291 | cis-4-(4-(4-(3,5-dimethylmorpholin...)
Affinity DataIC50:  18nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320421(CHEMBL1083337 | N-benzyl-1-(4-(1-cyclopropyl-4-(hy...)
Affinity DataIC50:  20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320430(CHEMBL1082314 | N-hydroxy-4-(4-(4-(4-phenethylpipe...)
Affinity DataIC50:  25nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320420(1-(4-(4-(hydroxycarbamoyl)tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50:  25nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320441(CHEMBL1082645 | N-hydroxy-4-(4-(4-(4-(pyrazin-2-yl...)
Affinity DataIC50:  27nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320444(1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piper...)
Affinity DataIC50:  28nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320428(CHEMBL1082658 | N-hydroxy-4-(4-(4-(4-isopropylpipe...)
Affinity DataIC50:  28nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320440(CHEMBL1082789 | N-hydroxy-4-(4-(4-(4-(pyridin-4-yl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320419(CHEMBL1083030 | N-allyl-1-(4-(4-(hydroxycarbamoyl)...)
Affinity DataIC50:  35nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320431(CHEMBL1083607 | N-hydroxy-4-(4-(4-(4-(2-hydroxyeth...)
Affinity DataIC50:  40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320429(CHEMBL1083606 | N-hydroxy-4-(4-(4-(4-(2-methoxyeth...)
Affinity DataIC50:  45nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320425(4-(4-(4-(3,5-dimethylpiperazine-1-carbonyl)piperid...)
Affinity DataIC50:  50nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320427(4-(4-(4-(4-acetylpiperazine-1-carbonyl)piperidin-1...)
Affinity DataIC50:  50nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320445(4-(4-(4-(4-(2,3-dimethylphenyl)piperazine-1-carbon...)
Affinity DataIC50:  70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320432(4-(4-(4-(4-(2-(dimethylamino)ethyl)piperazine-1-ca...)
Affinity DataIC50:  90nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320443(4-(4-(4-(4-(2,3-dimethylphenyl)piperazine-1-carbon...)
Affinity DataIC50:  160nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  370nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320445(4-(4-(4-(4-(2,3-dimethylphenyl)piperazine-1-carbon...)
Affinity DataIC50:  400nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320444(1-cyclopropyl-4-(4-(4-(4-(2,3-dimethylphenyl)piper...)
Affinity DataIC50:  550nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320436(4-(4-(4-(4-(4-acetylphenyl)piperazine-1-carbonyl)p...)
Affinity DataIC50:  700nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320430(CHEMBL1082314 | N-hydroxy-4-(4-(4-(4-phenethylpipe...)
Affinity DataIC50:  900nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320441(CHEMBL1082645 | N-hydroxy-4-(4-(4-(4-(pyrazin-2-yl...)
Affinity DataIC50:  900nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320442(CHEMBL1085257 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320433(4-(4-(4-(4-(2-fluorophenyl)piperazine-1-carbonyl)p...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320439(CHEMBL1084298 | N-hydroxy-4-(4-(4-(4-(pyrimidin-2-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320435(4-(4-(4-(4-(4-fluorophenyl)piperazine-1-carbonyl)p...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320425(4-(4-(4-(3,5-dimethylpiperazine-1-carbonyl)piperid...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320440(CHEMBL1082789 | N-hydroxy-4-(4-(4-(4-(pyridin-4-yl...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320420(1-(4-(4-(hydroxycarbamoyl)tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320422(CHEMBL1082324 | N-hydroxy-4-(4-(4-(1,2,3,4-tetrahy...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320423(4-(4-(4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320427(4-(4-(4-(4-acetylpiperazine-1-carbonyl)piperidin-1...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320419(CHEMBL1083030 | N-allyl-1-(4-(4-(hydroxycarbamoyl)...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320421(CHEMBL1083337 | N-benzyl-1-(4-(1-cyclopropyl-4-(hy...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320438(CHEMBL1084024 | N-hydroxy-4-(4-(4-(4-(pyridin-2-yl...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320434(CHEMBL1083584 | N-hydroxy-4-(4-(4-(4-(2-methoxyphe...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320428(CHEMBL1082658 | N-hydroxy-4-(4-(4-(4-isopropylpipe...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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