Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50039236
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320821(CHEMBL1163809 | N-(4-(3-(3-aminopropanamido)phenyl...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322292(CHEMBL1171484 | N-{3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322307(CHEMBL1169901 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322300(CHEMBL1173644 | N-{3-Cyano-4-[3-(1,4-diazepan-1-yl...)
Affinity DataIC50:  7.30nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320810(CHEMBL1165222 | N-(4-(3-(3-aminopropanamido)phenyl...)
Affinity DataIC50:  7.40nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322309(CHEMBL1170903 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  7.90nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322313(CHEMBL1170896 | rac-N-[3-Cyano-4-(3-{[3-(ethylamin...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322293(CHEMBL1170911 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  8.40nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322319(CHEMBL1170692 | rac-N-{3-Cyano-6-(4-fluoro-2-hydro...)
Affinity DataIC50:  9.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322303(CHEMBL1170870 | N-{3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  9.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322316(CHEMBL1170468 | N-[3-Cyano-4-{3-[(N-ethyl-N-methyl...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322310(CHEMBL1170904 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322308(CHEMBL1169902 | N-[3-Cyano-4-{3-[(N,N-dimethyl-bet...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322318(CHEMBL1170685 | rac-N-[3-Cyano-4-(3-{[3-(ethylamin...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322302(CHEMBL1173008 | N-{3-Cyano-4-[3-(4-ethylpiperazin-...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322295(CHEMBL1171977 | N-[3-Cyano-4-{3-[(N,N-dimethylglyc...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322289(CHEMBL1171294 | rac-N-[3-Cyano-6-(4-fluoro-2-hydro...)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322301(CHEMBL1172940 | N-{3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322297(CHEMBL1171296 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322294(CHEMBL1171102 | N-(3-{3-Cyano-6-(4-fluoro-2-hydrox...)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322317(CHEMBL1170684 | N-[3-Cyano-4-{3-[(N,N-diethyl-beta...)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322312(CHEMBL1170895 | rac-N-[3-Cyano-4-(3-{[3-(diethylam...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322290(CHEMBL1171097 | N-{3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322305(CHEMBL1173438 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322311(CHEMBL1170894 | rac-N-[3-Cyano-4-(3-{[3-(dimethyla...)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322291(CHEMBL1171483 | N-[3-Cyano-4-(3-{[2-(dimethylamino...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322307(CHEMBL1169901 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322306(CHEMBL1173512 | N-[3-Cyano-4-{3-[(4-ethylpiperazin...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322314(CHEMBL1171797 | rac-N-[3-Cyano-4-(3-{[3-(diethylam...)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322304(CHEMBL1173070 | N-{3-Cyano-4-[3-(1,4-diazepan-1-yl...)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322293(CHEMBL1170911 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322309(CHEMBL1170903 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322298(CHEMBL1171663 | N-[3-Cyano-4-(3-{[2-(dimethylamino...)
Affinity DataIC50:  30nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322296(CHEMBL1171104 | N-[3-Cyano-4-{3-[(N,N-diethylglycy...)
Affinity DataIC50:  30nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322310(CHEMBL1170904 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  38nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322308(CHEMBL1169902 | N-[3-Cyano-4-{3-[(N,N-dimethyl-bet...)
Affinity DataIC50:  47nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322302(CHEMBL1173008 | N-{3-Cyano-4-[3-(4-ethylpiperazin-...)
Affinity DataIC50:  47nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322295(CHEMBL1171977 | N-[3-Cyano-4-{3-[(N,N-dimethylglyc...)
Affinity DataIC50:  130nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322315(CHEMBL1169893 | N-(3-cyano-4-(3-(2-(dimethylamino)...)
Affinity DataIC50:  180nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  930nMAssay Description:Antagonist activity at human GPR54 receptor assessed as inhibition of metastin-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed