Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 50039257
TargetBeta-secretase 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM16047((4S)-4-[(2S)-2-[(2R,4S,5S)-5-[(2S)-2-[(2S)-2-[(4S)...)
Affinity DataIC50:  250nMAssay Description:Inhibition of BACE1 at 20 ug/ml by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50323879(-(2-(2-(6-Aminohexylamino)ethoxy)-5-bromophenyl)-3...)
Affinity DataIC50:  2.78E+4nMAssay Description:Inhibition of BACE1 at 20 ug/ml by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50323876(1-(5-Bromo-2-(2-(hexylamino)ethoxy)phenyl)-3-(2-ch...)
Affinity DataIC50:  2.94E+4nMAssay Description:Inhibition of BACE1 at 20 ug/ml by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50323878(1-(5-Bromo-2-(2-(cyclopropylamino)ethoxy)phenyl)-3...)
Affinity DataIC50:  3.76E+4nMAssay Description:Inhibition of BACE1 at 20 ug/ml by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50323877(1-(5-Bromo-2-(2-(5-hydroxypentylamino)ethoxy)pheny...)
Affinity DataIC50: >4.24E+4nMAssay Description:Inhibition of BACE1 at 20 ug/ml by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50323875(1-(5-Bromo-2-(2-(cyclohexylamino)ethoxy)phenyl)-3-...)
Affinity DataIC50: >4.28E+4nMAssay Description:Inhibition of BACE1 at 20 ug/ml by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50323874(1-(5-Bromo-2-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(...)
Affinity DataIC50: >4.42E+4nMAssay Description:Inhibition of BACE1 at 20 ug/ml by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50323880(1-(2-(2-(3-Aminopropylamino)ethoxy)-5-bromophenyl)...)
Affinity DataIC50: >4.52E+4nMAssay Description:Inhibition of BACE1 at 20 ug/ml by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed