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Found 24 Enz. Inhib. hit(s) with all data for entry = 50032169
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325328(4-((1H-imidazol-1-yl)methyl)phenyl biphenyl-4-sulf...)
Affinity DataIC50:  10nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296971(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)
Affinity DataIC50:  14nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325329(4-((1H-imidazol-1-yl)methyl)phenyl 4-ethylbenzenes...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325330(4-((1H-imidazol-1-yl)methyl)phenyl 4-propylbenzene...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296969(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296976(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)
Affinity DataIC50:  34nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325331(4-((1H-imidazol-1-yl)methyl)phenyl 4-butylbenzenes...)
Affinity DataIC50:  40nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296969(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)
Affinity DataIC50:  40nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325331(4-((1H-imidazol-1-yl)methyl)phenyl 4-butylbenzenes...)
Affinity DataIC50:  70nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325328(4-((1H-imidazol-1-yl)methyl)phenyl biphenyl-4-sulf...)
Affinity DataIC50:  100nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325329(4-((1H-imidazol-1-yl)methyl)phenyl 4-ethylbenzenes...)
Affinity DataIC50:  110nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325332(4-((1H-imidazol-1-yl)methyl)phenyl 4-pentylbenzene...)
Affinity DataIC50:  130nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325332(4-((1H-imidazol-1-yl)methyl)phenyl 4-pentylbenzene...)
Affinity DataIC50:  160nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188092(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)
Affinity DataIC50:  164nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296971(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)
Affinity DataIC50:  200nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  206nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188092(1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...)
Affinity DataIC50:  730nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50296976(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50325330(4-((1H-imidazol-1-yl)methyl)phenyl 4-propylbenzene...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188086(4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM50188086(4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  2.66E+3nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM7887(1-Benzylimidazole (BI) | 1-benzyl-1H-imidazole | 1...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland

Curated by ChEMBL
LigandPNGBDBM7887(1-Benzylimidazole (BI) | 1-benzyl-1H-imidazole | 1...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed