Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50032174
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325446(CHEMBL1222573 | cis-3-amino-N-(7-chloro-1-oxo-1,2-...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325431((S)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  12nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325444(CHEMBL1222571 | cis-4-amino-N-(7-chloro-1-oxo-1,2-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325434((R)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319636(CHEMBL1084107 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325437((S)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  20nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325439((S)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)...)
Affinity DataIC50:  25nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319633(2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)
Affinity DataIC50:  26nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319721(CHEMBL1085082 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  28nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319720(CHEMBL1083113 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)
Affinity DataIC50:  31nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325441((S)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)...)
Affinity DataIC50:  35nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319722((R)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)...)
Affinity DataIC50:  67nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325436((R)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  110nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319718(2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)
Affinity DataIC50:  120nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325440((R)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)...)
Affinity DataIC50:  130nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325442((S)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)...)
Affinity DataIC50:  180nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325432((R)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  240nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325445(CHEMBL1222572 | cis-3-amino-N-(7-chloro-1-oxo-1,2-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325443(CHEMBL1222570 | trans-4-amino-N-(7-chloro-1-oxo-1,...)
Affinity DataIC50:  330nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325433((S)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  340nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325438((R)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  400nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325435((S)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...)
Affinity DataIC50:  845nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325447(CHEMBL1222574 | cis-N-(7-chloro-1-oxo-1,2-dihydroi...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed