Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50032305
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326904(8-(2,4-Difluorophenyl)-3-(2,4-difluorophenylamino)...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326917(CHEMBL1254901 | N-Cyclopropyl-3-(8-(2,4-difluoroph...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326925(3-(8-(2-Chloro-5-fluorophenyl)-1-methyl-2-oxo-1,2-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326921(3-(8-(2-Chlorophenyl)-1-methyl-2-oxo-1,2-dihydropy...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326903(8-(2,4-Difluorophenyl)-3-(4-fluorophenylamino)-1-m...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326918(4-Chloro-N-cyclopropyl-3-(8-(2,4-difluorophenyl)-1...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326914(3-(8-(2,4-Difluorophenyl)-1-methyl-2-oxo-1,2-dihyd...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326920(CHEMBL1254647 | N-Cyclopropyl-4-methyl-3-(1-methyl...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326915(CHEMBL1254989 | N-Cyclopropyl-3-(8-(2,4-difluoroph...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326913(3-(8-(2,4-Difluorophenyl)-1-methyl-2-oxo-1,2-dihyd...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326924(CHEMBL1254814 | N-Cyclopropyl-3-(8-(2-fluoro-4-(tr...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326923(CHEMBL1254732 | N-Cyclopropyl-3-(8-(4-fluoro-2-met...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326916(3-(8-(2,4-Difluorophenyl)-1-methyl-2-oxo-1,2-dihyd...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326922(CHEMBL1254731 | N-Cyclopropyl-4-methyl-3-(1-methyl...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326911(3-(2,4-Difluorobenzyl)-8-(2,4-difluorophenyl)-1-me...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326909(3-(2,4-Difluorophenoxy)-8-(2,4-difluorophenyl)-1-m...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326919(CHEMBL1254572 | N-Cyclopropyl-4-(8-(2,4-difluoroph...)
Affinity DataIC50:  14.5nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326910(3-(4-Fluorobenzyl)-8-(2,4-difluorophenyl)-1-methyl...)
Affinity DataIC50:  55.8nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326908(8-(2,4-Difluorophenyl)-3-(4-fluorophenoxy)-1-methy...)
Affinity DataIC50:  78nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326906(8-(2,4-Difluorophenyl)-3-(3,5-difluoropyridin-2-yl...)
Affinity DataIC50:  111nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326907(8-(2,4-Difluorophenyl)-3-((4-fluorophenyl)(methyl)...)
Affinity DataIC50:  299nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326905(8-(2,4-Difluorophenyl)-3-(5-fluoropyridin-2-ylamin...)
Affinity DataIC50:  328nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50326912(3-(8-(2,4-Difluorophenyl)-1-methyl-2-oxo-1,2-dihyd...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed