Compile Data Set for Download or QSAR
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Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50032483
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329956(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329959((6-chloro-5-methyl-3-(2-(1-methyl-1H-1,2,4-triazol...)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329958((6-chloro-5-methyl-3-(2-(1-methyl-1H-1,2,4-triazol...)
Affinity DataIC50:  0.840nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329957(((3R,4R)-1-tert-butyl-3-(2,4-difluorophenyl)piperi...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329961(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329953(1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329954(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329955((3-(2-(1H-1,2,3-triazol-5-yl)propan-2-yl)-6-chloro...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329960((3-(2-(1,3,4-oxadiazol-2-yl)propan-2-yl)-6-chloro-...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329960((3-(2-(1,3,4-oxadiazol-2-yl)propan-2-yl)-6-chloro-...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329962(CHEMBL404696 | N-((S)-1-(2-(1-((3R,4S)-1-tert-buty...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329954(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329955((3-(2-(1H-1,2,3-triazol-5-yl)propan-2-yl)-6-chloro...)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329956(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329957(((3R,4R)-1-tert-butyl-3-(2,4-difluorophenyl)piperi...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329960((3-(2-(1,3,4-oxadiazol-2-yl)propan-2-yl)-6-chloro-...)
Affinity DataEC50:  211nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329959((6-chloro-5-methyl-3-(2-(1-methyl-1H-1,2,4-triazol...)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329962(CHEMBL404696 | N-((S)-1-(2-(1-((3R,4S)-1-tert-buty...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329960((3-(2-(1,3,4-oxadiazol-2-yl)propan-2-yl)-6-chloro-...)
Affinity DataEC50:  211nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329961(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329953(1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329958((6-chloro-5-methyl-3-(2-(1-methyl-1H-1,2,4-triazol...)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed