Compile Data Set for Download or QSAR
Report error Found 137 Enz. Inhib. hit(s) with all data for entry = 50032613
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331916BDBM50331916((S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  0.400nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331917BDBM50331917((R)-N-(2-hydroxy-1-phenylethyl)-2-(2-oxo-4-pheneth...)
Affinity DataKi:  0.440nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331914BDBM50331914(2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  1nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331913BDBM50331913(2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331911BDBM50331911((S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  1.70nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331917BDBM50331917((R)-N-(2-hydroxy-1-phenylethyl)-2-(2-oxo-4-pheneth...)
Affinity DataKi:  2.80nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331914BDBM50331914(2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  4.5nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331913BDBM50331913(2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  5.10nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331917BDBM50331917((R)-N-(2-hydroxy-1-phenylethyl)-2-(2-oxo-4-pheneth...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331917BDBM50331917((R)-N-(2-hydroxy-1-phenylethyl)-2-(2-oxo-4-pheneth...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331916BDBM50331916((S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  7.40nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331916BDBM50331916((S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331920BDBM50331920(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  10nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331933BDBM50331933(2-(3-(3-methylisoxazol-5-yl)-2-oxo-4-phenethyl-1,2...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331914BDBM50331914(2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331914BDBM50331914(2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331911BDBM50331911((S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331911BDBM50331911((S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  15nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331929BDBM50331929(1-((2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydro...)
Affinity DataKi:  17nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331913BDBM50331913(2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331910BDBM50331910(1-benzyl-3-((2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331916BDBM50331916((S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331908BDBM50331908(N-benzyl-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2...)
Affinity DataKi:  21nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331911BDBM50331911((S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331913BDBM50331913(2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroq...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331933BDBM50331933(2-(3-(3-methylisoxazol-5-yl)-2-oxo-4-phenethyl-1,2...)
Affinity DataKi:  31nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331908BDBM50331908(N-benzyl-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331920BDBM50331920(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  41nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331912BDBM50331912((R)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  60nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331908BDBM50331908(N-benzyl-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2...)
Affinity DataKi:  61nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331910BDBM50331910(1-benzyl-3-((2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331929BDBM50331929(1-((2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydro...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331910BDBM50331910(1-benzyl-3-((2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  68nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331919BDBM50331919(2-(2-oxo-4-(phenoxymethyl)-3-(thiazol-2-yl)-1,2-di...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331926BDBM50331926(N-benzyl-2-(1-methyl-3-(methylsulfonyl)-2-oxo-4-ph...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331919BDBM50331919(2-(2-oxo-4-(phenoxymethyl)-3-(thiazol-2-yl)-1,2-di...)
Affinity DataKi:  71nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331919BDBM50331919(2-(2-oxo-4-(phenoxymethyl)-3-(thiazol-2-yl)-1,2-di...)
Affinity DataKi:  81nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331908BDBM50331908(N-benzyl-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331920BDBM50331920(2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,...)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331926BDBM50331926(N-benzyl-2-(1-methyl-3-(methylsulfonyl)-2-oxo-4-ph...)
Affinity DataKi:  159nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331912BDBM50331912((R)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331921BDBM50331921(N-(3,4-dichlorobenzyl)-2-(3-(methylsulfonyl)-2-oxo...)
Affinity DataKi:  172nMAssay Description:Antagonist activity at adenosien A2B receptor in human HMC-1 cells assessed as inhibition of NECA-induced IL-8 release after 6 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331919BDBM50331919(2-(2-oxo-4-(phenoxymethyl)-3-(thiazol-2-yl)-1,2-di...)
Affinity DataKi:  183nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331931BDBM50331931(2-(2-oxo-4-phenethyl-3-(pyridin-3-yl)-1,2-dihydroq...)
Affinity DataKi:  187nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331921BDBM50331921(N-(3,4-dichlorobenzyl)-2-(3-(methylsulfonyl)-2-oxo...)
Affinity DataKi:  211nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331909BDBM50331909(N-((2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydro...)
Affinity DataKi:  291nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331921BDBM50331921(N-(3,4-dichlorobenzyl)-2-(3-(methylsulfonyl)-2-oxo...)
Affinity DataKi:  315nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331912BDBM50331912((R)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihy...)
Affinity DataKi:  320nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331907BDBM50331907(N-benzyl-2-(3-(furan-2-yl)-2-oxo-4-phenethyl-1,2-d...)
Affinity DataKi:  330nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331906BDBM50331906(2-(3-cyano-2-oxo-4-phenethyl-1,2-dihydroquinolin-6...)
Affinity DataKi:  338nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor transfected in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
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