Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50032677
TargetGlutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA2(R)o expressed in sS9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA3o expressed in sS9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA1o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA4o expressed in sS9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]AMPA from GluA2-S1S2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA1o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA1o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataKi:  348nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA2(R)o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataKi:  370nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA2(R)o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK1(Q)1b expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataKi:  2.43E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK1(Q)1b expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataKi:  3.23E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK2(VCR)a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataKi:  4.48E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK1(Q)1b expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataKi:  4.52E+3nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA3o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataKi:  6.80E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK1(Q)1b expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataKi:  1.19E+4nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA4o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataKi:  1.35E+4nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA4o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataKi:  2.75E+4nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA3o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataKi:  2.98E+4nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  4.27E+4nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataKi:  9.05E+4nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA3o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA2(R)o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA1o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK2(VCR)a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA4o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK2(VCR)a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM17662((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK2(VCR)a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at rat recombinant GluA2(Q)i expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  2.70E+6nMAssay Description:Agonist activity at rat recombinant GluA3i expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat recombinant GluA4i expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataEC50:  8.28E+4nMAssay Description:Agonist activity at rat recombinant GluA1i expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataEC50:  3.46E+4nMAssay Description:Agonist activity at rat recombinant GluA2(Q)i expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50027828((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...)
Affinity DataEC50:  6.37E+5nMAssay Description:Agonist activity at rat recombinant GluA3i expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  4.70E+3nMAssay Description:Agonist activity at rat recombinant GluA1i expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  1.30E+6nMAssay Description:Agonist activity at rat recombinant GluA4i expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed