Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50032788
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334712BDBM50334712((R,E)-3-(2-Fluoro-benzenesulfonyl)-thiazolidine-2-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334712BDBM50334712((R,E)-3-(2-Fluoro-benzenesulfonyl)-thiazolidine-2-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334708BDBM50334708((E)-3-[(2-Fluorophenyl)sulfonyl]-N-[5-(aminocarbon...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334708BDBM50334708((E)-3-[(2-Fluorophenyl)sulfonyl]-N-[5-(aminocarbon...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334709BDBM50334709(3-(3-Fluoro-benzenesulfonyl)-thiazolidine-2-carbox...)
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334704BDBM50334704(3-(3,4-Dichloro-benzenesulfonyl)-thiazolidine-2-ca...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334705BDBM50334705(3-Benzenesulfonyl-thiazolidine-2-carboxylic acid(5...)
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334706BDBM50334706(3-(Toluene-4-sulfonyl)-thiazolidine-2-carboxylic a...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334694BDBM50334694(3-Benzenesulfonyl-thiazolidine-2-carboxylic acid a...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334714BDBM50334714((R)-1-(2-Fluoro-benzenesulfonyl)-pyrrolidine-2-car...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334699BDBM50334699(3-(2-Fluoro-benzenesulfonyl)-thiazolidine-2-carbox...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334700BDBM50334700(3-(4-Chloro-benzenesulfonyl)-thiazolidine-2-carbox...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334701BDBM50334701(3-(3,4-Dichloro-benzenesulfonyl)-thiazolidine-2-ca...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334710BDBM50334710(3-(4-Fluoro-benzenesulfonyl)-thiazolidine-2-carbox...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334709BDBM50334709(3-(3-Fluoro-benzenesulfonyl)-thiazolidine-2-carbox...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334711BDBM50334711((S)-3-(2-Fluoro-benzenesulfonyl)-thiazolidine-2-ca...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334711BDBM50334711((S)-3-(2-Fluoro-benzenesulfonyl)-thiazolidine-2-ca...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334707BDBM50334707(3-(4-Methoxy-benzenesulfonyl)-thiazolidine-2-carbo...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334695BDBM50334695(3-(Toluene-4-sulfonyl)-thiazolidine-2-carboxylic a...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334698BDBM50334698(3-(4-Fluoro-benzenesulfonyl)-thiazolidine-2-carbox...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334689BDBM50334689(3-Benzyl-thiazolidine-2-carboxylic acid adamantan-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334713BDBM50334713((S)-1-(2-Fluoro-benzenesulfonyl)-pyrrolidine-2-car...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334696BDBM50334696(3-(4-Methoxy-benzenesulfonyl)-thiazolidine-2-carbo...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334707BDBM50334707(3-(4-Methoxy-benzenesulfonyl)-thiazolidine-2-carbo...)
Affinity DataIC50: 57nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334692BDBM50334692(3-Benzoyl-thiazolidine-2-carboxylic acid adamantan...)
Affinity DataIC50: 63nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334705BDBM50334705(3-Benzenesulfonyl-thiazolidine-2-carboxylic acid(5...)
Affinity DataIC50: 67nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334710BDBM50334710(3-(4-Fluoro-benzenesulfonyl)-thiazolidine-2-carbox...)
Affinity DataIC50: 76nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334697BDBM50334697(3-(4-tert-Butyl-benzenesulfonyl)-thiazolidine-2-ca...)
Affinity DataIC50: 149nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334703BDBM50334703(4-{[3-(3,4-Dichloro-benzenesulfonyl)-thiazolidine-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334708BDBM50334708((E)-3-[(2-Fluorophenyl)sulfonyl]-N-[5-(aminocarbon...)
Affinity DataIC50: 171nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334708BDBM50334708((E)-3-[(2-Fluorophenyl)sulfonyl]-N-[5-(aminocarbon...)
Affinity DataIC50: 171nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50247012BDBM50247012(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)
Affinity DataIC50: 250nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50247012BDBM50247012(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334691BDBM50334691(2-(Adamantan-2-ylcarbamoyl)-thiazolidine-3-carboxy...)
Affinity DataIC50: 554nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334702BDBM50334702(3-(3,4-Dichloro-benzenesulfonyl)-thiazolidine-2-ca...)
Affinity DataIC50: 683nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334706BDBM50334706(3-(Toluene-4-sulfonyl)-thiazolidine-2-carboxylic a...)
Affinity DataIC50: 842nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334693BDBM50334693(Thiazolidine-2,3-dicarboxylic acid 2-adamantan-2-y...)
Affinity DataIC50: 945nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334690BDBM50334690(Thiazolidine-2-carboxylic acid adamantan-2-ylamide...)
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed