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Found 60 Enz. Inhib. hit(s) with all data for entry = 50032796
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334916(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334920((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334919((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334920((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334917(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334917(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334767((2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334767((2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334925((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334925((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334767((2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)
Affinity DataIC50:  107nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  116nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334922(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)
Affinity DataIC50:  122nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334925((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  128nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334919((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  132nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  138nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334923(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  177nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334915(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)
Affinity DataIC50:  246nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334920((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  250nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334926((S)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  309nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334922(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)
Affinity DataIC50:  436nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334924((S)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  465nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334919((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  601nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334921(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)
Affinity DataIC50:  605nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334915(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)
Affinity DataIC50:  650nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334915(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)
Affinity DataIC50:  926nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334917(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  934nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334923(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  985nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334923(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334920((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334925((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334919((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334924((S)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334922(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334924((S)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334921(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334921(1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquinolin-...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334917(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334926((S)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  3.09E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334919((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  3.25E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334918((R)-1-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  4.87E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334916(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)
Affinity DataIC50:  5.03E+3nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334926((S)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  5.56E+3nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334920((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  6.02E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334916(1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrah...)
Affinity DataIC50:  7.14E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334917(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334920((R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-te...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334917(1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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