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Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50032854
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)
Affinity DataIC50:  20nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50054601(5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazole...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50335631(2-Nitro-3-oxo-3-[(4-trifluoromethyl)phenyl]aminopr...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50335629(2-Nitro-3-oxo-3-(biphenyl-4-yl)aminopropionitrile ...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50335630(2-Hydroxyimino-3-oxo-3-[4-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50335632(2-Nitro-3-(4-nitrophenyl)amino-3-oxopropionitrile ...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed