Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50032733
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333890(N-((1H-benzo[d]imidazol-2-yl)methyl)-N-((4-(aminom...)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333893(N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(2-(aminome...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333882(4-((((1H-benzo[d]imidazol-2-yl)methyl)(5,6,7,8-tet...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333894([4-((((1H-benzo[d]imidazol-2-yl)methyl(5,6,7,8-tet...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333895([4-((((1H-benzo[d]imidazol-2-yl)methyl(5,6,7,8-tet...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333888(N-((1H-benzo[d]imidazol-2-yl)methyl)-N-((3-(aminom...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333884((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-(ami...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333881(4-((((1H-benzo[d]imidazol-2-yl)methyl)(5,6,7,8-tet...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333883((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-((2-(am...)
Affinity DataIC50: 19.8nMAssay Description:Displacement of [125I]SDF-1 from CXCR4 in human CEM-CCRF cells expressing CD4 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333889(N-((1H-benzo[d]imidazol-2-yl)methyl)-N-((2-(aminom...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333883((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-((2-(am...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333896(N-((1H-benzo[d]imidazol-2-yl)methyl-N-(2-(aminomet...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333885((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-(ami...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50315290(N-[(1H-Benzo[d]midazol-2-yl)methyl]-N-(2-(aminomet...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333898(Methyl-4-((((1H-benzo[d]imidazol-2-yl)methyl)(5,6,...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333885((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-(ami...)
Affinity DataIC50: 44.5nMAssay Description:Displacement of [125I]SDF-1 from CXCR4 in human CEM-CCRF cells expressing CD4 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333892(N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(2-(aminome...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333887(N-((1H-benzo[d]imidazol-2-yl)methyl)-N-((2-(aminom...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333884((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-(ami...)
Affinity DataIC50: 88.9nMAssay Description:Displacement of [125I]SDF-1 from CXCR4 in human CEM-CCRF cells expressing CD4 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333897(4-((((1H-benzo[d]imidazole-2-yl)methyl)(5,6,7,8-te...)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333886(N-((1H-benzo[d]imidazol-2-yl)methyl)-N-((4-(aminom...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50333891(N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(2-(aminome...)
Affinity DataIC50: 219nMAssay Description:Antagonist activity at CXCR4 in human CEM-CCRF cells expressing CD4 assessed as inhibition of SDF-1-induced Ca2+ signalingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed