Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50039333
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334942(1-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-in...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334936(CHEMBL1649665 | N-cyclopentyl-2-{4-[3-(trifluorome...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334935(1-{4-[1-(1-pyrrolidinylcarbonyl)cyclopropyl]phenyl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334936(CHEMBL1649665 | N-cyclopentyl-2-{4-[3-(trifluorome...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334948(CHEMBL1649654 | N-methyl-N-(2-phenylethyl)-4-[3-(t...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334939(1-({4-[3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-i...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334940(1-{4-[1-methyl-2-oxo-2-(1-pyrrolidinyl)ethyl]pheny...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334937(1-({2-Fluoro-4-[3-(trifluoromethyl)-4,5,6,7-tetrah...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334949(1-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-in...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334947(CHEMBL1649655 | N,N-dimethyl-4-[3-(trifluoromethyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334946(1-{4-[2-OXO-2-(1-PYRROLIDINYL)ETHYL]PHENYL}-3-( TR...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334948(CHEMBL1649654 | N-methyl-N-(2-phenylethyl)-4-[3-(t...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334938(CHEMBL1649672 | N-({4-[3-(trifluoromethyl)-4,5,6,7...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334941(1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-4...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334945(1-{4-[1,1-difluoro-2-oxo-2-(1-pyrrolidinyl)ethyl]p...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334942(1-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-in...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334939(1-({4-[3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-i...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334935(1-{4-[1-(1-pyrrolidinylcarbonyl)cyclopropyl]phenyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334943(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334932(CHEMBL1649660 | N-butyl-N-methyl-4-[3-(trifluorome...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334941(1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-4...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334950(CHEMBL1594422 | N,N-Dimethyl-4-[3-(trifluoromethyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334940(1-{4-[1-methyl-2-oxo-2-(1-pyrrolidinyl)ethyl]pheny...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334935(1-{4-[1-(1-pyrrolidinylcarbonyl)cyclopropyl]phenyl...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334944(1-{3-Fluoro-4-[2-oxo-2-(1-pyrrolidinyl)ethyl]pheny...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334931(CHEMBL1649663 | N,N-Dimethyl-2-{4-[3-(trifluoromet...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334938(CHEMBL1649672 | N-({4-[3-(trifluoromethyl)-4,5,6,7...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334932(CHEMBL1649660 | N-butyl-N-methyl-4-[3-(trifluorome...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334936(CHEMBL1649665 | N-cyclopentyl-2-{4-[3-(trifluorome...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334937(1-({2-Fluoro-4-[3-(trifluoromethyl)-4,5,6,7-tetrah...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334930(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334927(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334928(1-({2,6-Difluoro-4-[3-(trifluoromethyl)-6,7-dihydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334930(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334930(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334930(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334928(1-({2,6-Difluoro-4-[3-(trifluoromethyl)-6,7-dihydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334927(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334934(1-({4-[3-(Trifluoromethyl)-4,7-dihydropyrano[3,4-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334933(1-({4-[6-Methyl-3-(trifluoromethyl)-4,5,6,7-tetrah...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334930(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334928(1-({2,6-Difluoro-4-[3-(trifluoromethyl)-6,7-dihydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334933(1-({4-[6-Methyl-3-(trifluoromethyl)-4,5,6,7-tetrah...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334934(1-({4-[3-(Trifluoromethyl)-4,7-dihydropyrano[3,4-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334927(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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