Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50039337
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334975(CHEMBL1649924 | endo-methyl 3-(8-((S)-3-acetamido-...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334974(CHEMBL1649927 | endo-methyl 3-(8-((S)-3-(3-fluorop...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334973(CHEMBL1649926 | endo-methyl(S)-3-(3-(5-acetyl-2-me...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334978(CHEMBL1649922 | endo-methyl 3-(8-((S)-3-acetamido-...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334977(CHEMBL1649921 | endo-N-((S)-3-(3-(5-isobutyryl-2-m...)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334980(CHEMBL1649919 | endo-N-((S)-3-(3-(5-acetyl-2-methy...)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334979(CHEMBL1649920 | endo-N-((S)-3-(3-(2-methyl-5-propi...)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334971(CHEMBL1649913 | endo-N-((S)-3-(3-(2-methyl-1H-benz...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334976(CHEMBL1649925 | endo-methyl(S)-3-(3-(5-acetyl-2-me...)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334972(CHEMBL1649912 | endo-4,4-difluoro-N-((S)-3-(3-(5-i...)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334982(CHEMBL1649918 | endo-N-((S)-3-(3-(2-methyl-5-(meth...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334981(CHEMBL1649917 | endo-N-((S)-3-(3-(5-isopropyl-2-me...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334983(CHEMBL1649916 | endo-N-((S)-3-(3-(2,5-dimethyl-4,5...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334985(CHEMBL1649915 | endo-N-((S)-3-(3-(2-methyl-4,5,6,7...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334969(CHEMBL1649928 | endo-N-((S)-1-(3-fluorophenyl)-3-(...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334984(CHEMBL1649914 | endo-N-((S)-3-(3-(5-benzyl-2-methy...)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at CCR5 receptor expressed in HeLa-P4 cells co-expressing CD4 assessed as inhibition of infusion to HIV gp120 expressed in CHO-ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334970(CHEMBL1649929 | endo-N-((S)-1-(3-fluorophenyl)-3-(...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334971(CHEMBL1649913 | endo-N-((S)-3-(3-(2-methyl-1H-benz...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334968(CHEMBL1649910 | Methyl 1-endo-{8-[(3S)-3-(Acetamid...)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334972(CHEMBL1649912 | endo-4,4-difluoro-N-((S)-3-(3-(5-i...)
Affinity DataIC50:  4.23E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334966(CHEMBL1649930 | endo-N-((S)-1-(3-fluorophenyl)-3-(...)
Affinity DataIC50:  5.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334967(CHEMBL1649911 | endo-N-((S)-3-(3-(5-acetyl-2-methy...)
Affinity DataIC50:  5.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334963(CHEMBL1649933 | endo-N-((S)-1-(3-fluorophenyl)-3-(...)
Affinity DataIC50:  5.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334965(CHEMBL1649932 | endo-N-((S)-3-(3-(5-butyryl-2-meth...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334964(CHEMBL1649931 | N-{(1S)-3-[3-endo-(5-Isobutyryl-2-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed