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Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50039371
TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCytochrome P450 3A4(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50378887(ALPHA-CONIDENDRIN)
Affinity DataIC50:  200nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50378887(ALPHA-CONIDENDRIN)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335920((+)-Lariciresinol | (+/-)-lariciresinol | CHEMBL51...)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50240914((+)-secoisolariciresinol | CHEMBL368347)
Affinity DataIC50:  4.73E+4nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335921((7S,8S)-methoxy-3',7-epoxy-8,4'-oxyneoligna-4,9,9'...)
Affinity DataIC50:  5.42E+4nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335918((7R)-7-hydroxylariciresinol | CHEMBL1668112)
Affinity DataIC50:  6.65E+4nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335919(CHEMBL1668114 | taxiresinol)
Affinity DataIC50:  6.81E+4nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335919(CHEMBL1668114 | taxiresinol)
Affinity DataIC50:  8.56E+4nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50223783((+)-isolariciresinol | CHEMBL399512 | isolaricires...)
Affinity DataIC50:  9.77E+4nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335917((3S,4R)-4'-hydroxy-6,3'-dimethoxyisoflavan-4-ol | ...)
Affinity DataIC50:  9.95E+4nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335917((3S,4R)-4'-hydroxy-6,3'-dimethoxyisoflavan-4-ol | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50223783((+)-isolariciresinol | CHEMBL399512 | isolaricires...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50240914((+)-secoisolariciresinol | CHEMBL368347)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335920((+)-Lariciresinol | (+/-)-lariciresinol | CHEMBL51...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335921((7S,8S)-methoxy-3',7-epoxy-8,4'-oxyneoligna-4,9,9'...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335918((7R)-7-hydroxylariciresinol | CHEMBL1668112)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed