Compile Data Set for Download or QSAR
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Found 42 Enz. Inhib. hit(s) with all data for entry = 50039339
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335008(5-Biphenyl-4-yl-4-(2-fluorophenyl)-N-methyl-4H-1,2...)
Affinity DataIC50:  83nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335006(2-(3-Biphenyl-4-yl-5-methyl-4H-1,2,4-triazole-4-yl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335008(5-Biphenyl-4-yl-4-(2-fluorophenyl)-N-methyl-4H-1,2...)
Affinity DataIC50:  110nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335001(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50:  190nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335004(3-Biphenyl-4-yl-4-(2-chlorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50:  190nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335010(3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-t...)
Affinity DataIC50:  220nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335010(3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-t...)
Affinity DataIC50:  230nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335007(2-(3-(biphenyl-4-yl)-5-methyl-4H-1,2,4-triazol-4-y...)
Affinity DataIC50:  240nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335006(2-(3-Biphenyl-4-yl-5-methyl-4H-1,2,4-triazole-4-yl...)
Affinity DataIC50:  260nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335004(3-Biphenyl-4-yl-4-(2-chlorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50:  280nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335012(3-Biphenyl-4-yl-5-methyl-4-(2-methylphenyl)-4H-1,2...)
Affinity DataIC50:  300nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335001(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50:  340nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335011(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-...)
Affinity DataIC50:  370nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335005(3-Biphenyl-4-yl-5-methyl-4-[2-(trifluoromethyl)phe...)
Affinity DataIC50:  390nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335009(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methoxy-4H-1,...)
Affinity DataIC50:  510nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335005(3-Biphenyl-4-yl-5-methyl-4-[2-(trifluoromethyl)phe...)
Affinity DataIC50:  600nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335007(2-(3-(biphenyl-4-yl)-5-methyl-4H-1,2,4-triazol-4-y...)
Affinity DataIC50:  680nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335012(3-Biphenyl-4-yl-5-methyl-4-(2-methylphenyl)-4H-1,2...)
Affinity DataIC50:  780nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50334998(3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...)
Affinity DataIC50:  880nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335013(3-Biphenyl-4-yl-4-(2-ethylphenyl)-5-methyl-4H-1,2,...)
Affinity DataIC50:  920nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335009(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methoxy-4H-1,...)
Affinity DataIC50:  990nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335023(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-(methylsulfan...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50334998(3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50114035(3-Biphenyl-4-yl-4-(2-methoxy-phenyl)-5-methyl-4H-[...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50114035(3-Biphenyl-4-yl-4-(2-methoxy-phenyl)-5-methyl-4H-[...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335022(3-Biphenyl-4-yl-4-(2-fluorophenyl)-4H-1,2,4-triazo...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335026(3-Biphenyl-4-yl-5-tert-butyl-4-(2-fluorophenyl)-4H...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335002(3-Biphenyl-4-yl-4-(3-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335011(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335014(3-Biphenyl-4-yl-5-methyl-4-(2-propylphenyl)-4H-1,2...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50334999(3-Biphenyl-4-yl-4-cyclohexyl-5-methyl-4H-1,2,4-tri...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335024(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-(methylsulfon...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335018(3-(4-Cyclohexylphenyl)-4-(2-fluorophenyl)-5-methyl...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335025(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-trifluorometh...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335016(4-Biphenyl-2-yl-3-biphenyl-4-yl-5-methyl-4H-1,2,4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335015(3-Biphenyl-4-yl-4-(2-isopropylphenyl)-5-methyl-4H-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335021(3-(Biphenyl-4-yl-methyl)-4-(2-fluorophenyl)-5-meth...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335003(3-Biphenyl-4-yl-4-(4-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335000(3-Biphenyl-4-yl-4-isopropyl-5-methyl-4H-1,2,4-tria...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335019(3-Biphenyl-2-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335020(3-Biphenyl-3-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(attus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335017(4-(2-Fluorophenyl)-3-methyl-5-phenyl-4H-1,2,4-tria...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed