Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50032779
Target5-hydroxytryptamine receptor 7(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098551BDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Affinity DataKi:  1nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334516BDBM50334516(1-benzyl-3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1H-...)
Affinity DataKi:  14nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334524BDBM50334524(1-benzyl-3-p-tolyl-4,5,6,7-tetrahydro-1H-pyrrolo[3...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334535BDBM50334535(1-benzyl-3-(4-chlorophenyl)-5-methyl-4,5,6,7-tetra...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334528BDBM50334528(1-benzyl-3-(4-fluorophenyl)-4,5,6,7-tetrahydro-1H-...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334518BDBM50334518(1-benzyl-3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1H-...)
Affinity DataKi:  107nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334521BDBM50334521(1-benzyl-3-(4-(trifluoromethyl)phenyl)-4,5,6,7-tet...)
Affinity DataKi:  167nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334517BDBM50334517(1-benzyl-3-phenyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334536BDBM50334536(1-benzyl-3-(4-chlorophenyl)-5-ethyl-4,5,6,7-tetrah...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334529BDBM50334529(1-benzyl-3-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1H...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334537BDBM50334537(1-benzyl-3-(4-chlorophenyl)-5-isopropyl-4,5,6,7-te...)
Affinity DataKi:  370nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334523BDBM50334523(1-benzyl-3-(4-nitrophenyl)-4,5,6,7-tetrahydro-1H-p...)
Affinity DataKi:  450nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334534BDBM50334534(1-(3-chlorobenzyl)-3-(4-chlorophenyl)-4,5,6,7-tetr...)
Affinity DataKi:  533nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334533BDBM50334533(1-(4-chlorobenzyl)-3-phenyl-4,5,6,7-tetrahydro-1H-...)
Affinity DataKi:  753nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334522BDBM50334522(1-benzyl-3-(2,4-dichlorophenyl)-4,5,6,7-tetrahydro...)
Affinity DataKi:  2.07E+3nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334527BDBM50334527(1-benzyl-3-(3-fluorophenyl)-4,5,6,7-tetrahydro-1H-...)
Affinity DataKi:  2.73E+3nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334520BDBM50334520(1-benzyl-3-(3,4-dichlorophenyl)-4,5,6,7-tetrahydro...)
Affinity DataKi:  4.47E+3nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334532BDBM50334532(1-(3-chlorobenzyl)-3-phenyl-4,5,6,7-tetrahydro-1H-...)
Affinity DataKi:  6.60E+3nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334526BDBM50334526(1-benzyl-3-(3-chlorophenyl)-4,5,6,7-tetrahydro-1H-...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334525BDBM50334525(1-benzyl-3-(4-tert-butylphenyl)-4,5,6,7-tetrahydro...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334519BDBM50334519(1-benzyl-3-(4-(trifluoromethoxy)phenyl)-4,5,6,7-te...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334530BDBM50334530(4-(1-benzyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]py...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334531BDBM50334531(1-(2-chlorobenzyl)-3-phenyl-4,5,6,7-tetrahydro-1H-...)
Affinity DataKi:  2.29E+4nMAssay Description:Displacement of [3H]5-CT from rat recombinant 5HT7 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed