Found 6 Enz. Inhib. hit(s) with all data for entry = 8143 
Affinity DataKi: 0.0750nM ΔG°: -57.8kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of peptide substrate cleavage by FXa was assayed against six concentrations of S2765 and six concentrations of apixaban. Typical assays we...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.140nM ΔG°: -57.4kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of peptide substrate cleavage by FXa was assayed against six concentrations of S2765 and six concentrations of apixaban. Typical assays we...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nM ΔG°: -57.0kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of peptide substrate cleavage by FXa was assayed against six concentrations of S2765 and six concentrations of apixaban. Typical assays we...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -56.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of peptide substrate cleavage by FXa was assayed against six concentrations of S2765 and six concentrations of apixaban. Typical assays we...More data for this Ligand-Target Pair
Affinity DataKi: 0.410nM ΔG°: -53.6kJ/molepH: 7.5 T: 2°CAssay Description:For comparison with the prothrombinase reaction the assays were also conducted with S2765 at 25 and 37°C in a similar buffer: 20 mM HEPES, pH 7.5 con...More data for this Ligand-Target Pair
Affinity DataKi: 0.720nM ΔG°: -54.3kJ/molepH: 7.5 T: 2°CAssay Description:For comparison with the prothrombinase reaction the assays were also conducted with S2765 at 25 and 37°C in a similar buffer: 20 mM HEPES, pH 7.5 con...More data for this Ligand-Target Pair
