Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50033081
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataIC50: 960nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) assessed as N-methyldihydronicotinamide oxidation per mg of protein a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM50339150(5,7-dihydroxy-2-(4-hydroxyphenyl)-3-((2R,3S,4S,5S,...)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) assessed as N-methyldihydronicotinamide oxidation per mg of protein a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM50339149(beta-(3,4-dihydroxyphenyl)ethyl-3-O-E-caffeoyl-O-[...)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM50339147(beta-(4-hydroxyphenyl)ethyl-4-O-E-caffeoyl-O-[beta...)
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM50339148(beta-(3,4-dihydroxyphenyl)ethyl-6-O-E-caffeoyl-O-[...)
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM50269516(Calceolarioside B | CHEMBL518414)
Affinity DataIC50: 3.53E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed