Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50032986
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337452BDBM50337452(2-(4-chloro-2-((2-(6-methyl-2-oxo-3-(2-(pyridin-2-...)
Affinity DataKi:  0.0150nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337453BDBM50337453(2-(4-chloro-2-((2-(6-methyl-2-oxo-3-(2-(pyridin-2-...)
Affinity DataKi:  0.125nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337470BDBM50337470(2-(2-(5-chloro-4-(2-(5-chloro-2-(2,2,2-trifluoroet...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337461BDBM50337461(N-(5-chloro-2-(2,2,2-trifluoroethoxy)benzyl)-2-(6-...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066333BDBM50066333((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  0.610nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337454BDBM50337454(N-(2,5-dichlorobenzyl)-2-(6-methyl-2-oxo-3-(2-(pyr...)
Affinity DataKi:  0.75nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337468BDBM50337468(2-(2-(5-chloro-4-(2-(2,5-dichlorobenzylamino)-2-ox...)
Affinity DataKi:  0.760nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337458BDBM50337458(N-(5-chloro-2-methylbenzyl)-2-(6-methyl-2-oxo-3-(2...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337466BDBM50337466(2-(2-(5-chloro-4-(2-(2-cyano-5-methoxybenzylamino)...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337467BDBM50337467(2-(2-(5-chloro-4-(2-(5-chloro-2-methylbenzylamino)...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337460BDBM50337460(N-(2-cyano-5-methylbenzyl)-2-(6-methyl-2-oxo-3-(2-...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337471BDBM50337471(2-(6-chloro-2-oxo-3-(2-(pyridin-2-yl)ethylamino)py...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337462BDBM50337462(N-(5-methyl-2-(2,2,2-trifluoroethoxy)benzyl)-2-(6-...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337459BDBM50337459(N-(2-cyano-5-methoxybenzyl)-2-(6-methyl-2-oxo-3-(2...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337469BDBM50337469(2-(2-(5-chloro-4-(2-(5-chloro-2-methoxybenzylamino...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337465BDBM50337465((+/-)-N-(2-cyano-5-methoxybenzyl)-2-(6-methyl-2-ox...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337456BDBM50337456(N-(5-chloro-2-methoxybenzyl)-2-(6-methyl-2-oxo-3-(...)
Affinity DataKi:  2nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337464BDBM50337464((+/-)-N-(5-chloro-2-methylbenzyl)-2-(6-methyl-2-ox...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337455BDBM50337455(N-(3-chlorobenzyl)-2-(6-methyl-2-oxo-3-(2-(pyridin...)
Affinity DataKi:  3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337463BDBM50337463((+/-)-N-(5-chloro-2-methoxybenzyl)-2-(6-methyl-2-o...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337457BDBM50337457(N-(2-methoxy-5-methylbenzyl)-2-(6-methyl-2-oxo-3-(...)
Affinity DataKi:  8nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed