Compile Data Set for Download or QSAR
maximum 50k data
Found 81 Enz. Inhib. hit(s) with all data for entry = 50032993
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337608(CHEMBL1683063 | cis-((1S,3R)-3-(3-ethyl-tetrahydro...)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337604(CHEMBL1683059 | Cis-((1S,3R)-1-isopropyl-3-(3-meth...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  2.80nMAssay Description:Binding affinity to mouse CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Rattus norvegicus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  2.90nMAssay Description:Binding affinity to rat CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337604(CHEMBL1683059 | Cis-((1S,3R)-1-isopropyl-3-(3-meth...)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337608(CHEMBL1683063 | cis-((1S,3R)-3-(3-ethyl-tetrahydro...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  5.30nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)
Affinity DataIC50:  5.70nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337605(CHEMBL1683060 | Cis-((1S,3R)-1-isopropyl-3-(3-meth...)
Affinity DataIC50:  5.70nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337618(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  6.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337618(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  6.20nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)
Affinity DataIC50:  6.90nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)
Affinity DataIC50:  7nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  8.40nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  8.90nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337622(((1S,3R)-1-ethyl-3-((3S,4S)-3-methoxy-tetrahydro-2...)
Affinity DataIC50:  9.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337605(CHEMBL1683060 | Cis-((1S,3R)-1-isopropyl-3-(3-meth...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337623(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human CCR5 receptor by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337609(CHEMBL1683064 | cis-((1S,3R)-3-(3-ethyl-tetrahydro...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337633(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337613(CHEMBL1683068 | cis-((1S,3R)-1-isopropyl-3-(3-meth...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337633(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  17nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337602(((1S,3R)-1-isopropyl-3-(tetrahydro-2H-pyran-4-ylam...)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337608(CHEMBL1683063 | cis-((1S,3R)-3-(3-ethyl-tetrahydro...)
Affinity DataIC50:  18nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337632(((1R,3R)-1-(3-fluoropropyl)-3-((3S,4S)-3-methoxy-t...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337626(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337614(CHEMBL1683069 | cis-((1S,3R)-3-(3-ethoxy-tetrahydr...)
Affinity DataIC50:  23nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)
Affinity DataIC50:  23nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337624(((1S,3R)-1-sec-butyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  23nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337618(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  27nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337606(CHEMBL1683061 | trans-((1S,3R)-1-isopropyl-3-(3-me...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337625(((1R,3R)-1-(cyclopropylmethyl)-3-((3S,4S)-3-methox...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337622(((1S,3R)-1-ethyl-3-((3S,4S)-3-methoxy-tetrahydro-2...)
Affinity DataIC50:  32nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337627(((1S,3R)-1-(ethoxymethyl)-3-((3S,4S)-3-methoxy-tet...)
Affinity DataIC50:  34nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  35nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337616(CHEMBL1683071 | cis-((1S,3R)-1-isopropyl-3-(3-(met...)
Affinity DataIC50:  36nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337632(((1R,3R)-1-(3-fluoropropyl)-3-((3S,4S)-3-methoxy-t...)
Affinity DataIC50:  40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337623(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  41nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337601(((1S,3R)-1-isopropyl-3-(tetrahydro-2H-pyran-4-ylam...)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337610(CHEMBL1683065 | trans-((1S,3R)-3-(3-ethyl-tetrahyd...)
Affinity DataIC50:  46nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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