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Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50033017
LigandPNGBDBM50338198(3-(2-morpholino-7-(pyridin-4-yl)-6,7-dihydro-5H-py...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50338199(5-(2-Morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50338200(3-(2-morpholino-7-(pyridin-3-yl)-6,7-dihydro-5H-py...)
Affinity DataIC50:  41nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50338196(3-(7-(1H-benzo[d]imidazol-6-yl)-2-morpholino-6,7-d...)
Affinity DataIC50:  77nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of PI3KC2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3KC2alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Vps34More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed