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Found 25 Enz. Inhib. hit(s) with all data for entry = 50039391
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336971(5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50:  30nMAssay Description:Inhibition of COX2 in mouse LPS-stimulated RAW264.7 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  30nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336964(4-[5-(3-Iodophenyl)-3-(trifluoromethyl)-1H-pyrazol...)
Affinity DataIC50:  40nMAssay Description:Inhibition of COX2 in mouse LPS-stimulated RAW264.7 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336971(5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50:  50nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336964(4-[5-(3-Iodophenyl)-3-(trifluoromethyl)-1H-pyrazol...)
Affinity DataIC50:  80nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336967(CHEMBL1672579 | ethyl 5-(4-iodophenyl)-1-(4-sulfam...)
Affinity DataIC50:  260nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336970(5-(3-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50:  320nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336966(CHEMBL1672578 | methyl 5-(4-iodophenyl)-1-(4-sulfa...)
Affinity DataIC50:  560nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336967(CHEMBL1672579 | ethyl 5-(4-iodophenyl)-1-(4-sulfam...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of COX2 in mouse LPS-stimulated RAW264.7 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336973(CHEMBL1672585 | methyl 5-(4-iodophenyl)-1-(4-(meth...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336965(CHEMBL1672577 | methyl 5-(3-iodophenyl)-1-(4-sulfa...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336973(CHEMBL1672585 | methyl 5-(4-iodophenyl)-1-(4-(meth...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336972(CHEMBL1672584 | methyl 5-(3-iodophenyl)-1-(4-(meth...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336971(5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336970(5-(3-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336968(3-(5-(3-iodophenyl)-1-(4-sulfamoylphenyl)-1H-pyraz...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336969(3-(5-(4-iodophenyl)-1-(4-sulfamoylphenyl)-1H-pyraz...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336968(3-(5-(3-iodophenyl)-1-(4-sulfamoylphenyl)-1H-pyraz...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50336972(CHEMBL1672584 | methyl 5-(3-iodophenyl)-1-(4-(meth...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336967(CHEMBL1672579 | ethyl 5-(4-iodophenyl)-1-(4-sulfam...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336966(CHEMBL1672578 | methyl 5-(4-iodophenyl)-1-(4-sulfa...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336965(CHEMBL1672577 | methyl 5-(3-iodophenyl)-1-(4-sulfa...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336964(4-[5-(3-Iodophenyl)-3-(trifluoromethyl)-1H-pyrazol...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50336969(3-(5-(4-iodophenyl)-1-(4-sulfamoylphenyl)-1H-pyraz...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed