Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50039394
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273338BDBM50273338((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338500BDBM50338500((S)-1-((1-benzyl-1H-1,2,3-triazol-5-yl)methyl)-5-(...)
Affinity DataIC50: 9nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338500BDBM50338500((S)-1-((1-benzyl-1H-1,2,3-triazol-5-yl)methyl)-5-(...)
Affinity DataKi:  10.5nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338491BDBM50338491((S)-1-((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H...)
Affinity DataKi:  14.5nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273337BDBM50273337((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50: 16.7nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338491BDBM50338491((S)-1-((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H...)
Affinity DataIC50: 17nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338489BDBM50338489((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 18nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338488BDBM50338488((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 21nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338486BDBM50338486((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 21nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338487BDBM50338487((S)-1-((1-(biphenyl-4-yl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50: 23nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338492BDBM50338492((S)-1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-5-(...)
Affinity DataIC50: 30nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338490BDBM50338490((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 44nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10318BDBM10318(5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}...)
Affinity DataIC50: 44nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338498BDBM50338498((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 70nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338494BDBM50338494((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 103nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10305BDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)
Affinity DataIC50: 120nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338495BDBM50338495((S)-1-((1-(biphenyl-4-yl)-1H-1,2,3-triazol-5-yl)me...)
Affinity DataIC50: 136nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338499BDBM50338499((S)-1-((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H...)
Affinity DataIC50: 136nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338501BDBM50338501((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 207nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338496BDBM50338496((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 213nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338493BDBM50338493((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 243nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338497BDBM50338497((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)
Affinity DataIC50: 267nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCaspase-3(Human)
University of Oslo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22817BDBM22817(5-nitro-2,3-dihydro-1H-indole-2,3-dione | CHEMBL11...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed