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Found 6 Enz. Inhib. hit(s) with all data for entry = 50033282
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342746(2-thienyl-sulfonamido-farnesylcysteine | CHEMBL177...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342745((R)-2-(5-(dimethylamino)naphthalene-1-sulfonamido)...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342747(3-nitrophenyl-sulfonamido-farnesylcysteine | CHEMB...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342748(4-fluoro-phenyl-sulfonamido-farnesylcysteine | CHE...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342744(CHEMBL1771292 | phenyl-sulfonamido-farnesylcystein...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342743((R)-2-(2-phenoxyphenylsulfonamido)-3-(3,7,11-trime...)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed