Compile Data Set for Download or QSAR
maximum 50k data
Found 218 Enz. Inhib. hit(s) with all data for entry = 50033172
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340800(3-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340794(CHEMBL1760685 | N-(4-(5-(1-(4-chlorophenyl)cyclobu...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50260908(3-(3-chloro-4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340801(2-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340811(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340803(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340830(3-chloro-4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-met...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340820(4-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340819(6-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340814(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50260908(3-(3-chloro-4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239407(3-(1-(4-chlorophenyl)cyclobutyl)-5,6,7,8,9,10-hexa...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340818(3-chloro-6-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340800(3-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340818(3-chloro-6-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340812(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340799(3-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50260623(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340802(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340799(3-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340808(CHEMBL1760690 | N-(3-chloro-4-(5-(1-(4-chloropheny...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340815(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340813(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340813(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340805(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340831(2-(3-chloro-4-(5-(1-(4-chlorophenyl)-3-fluorocyclo...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340816(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340812(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340808(CHEMBL1760690 | N-(3-chloro-4-(5-(1-(4-chloropheny...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340817(6-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340802(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340796(CHEMBL1760687 | N-(4-(5-(1-(4-chlorophenyl)cyclobu...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340814(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340823(CHEMBL1760674 | N-tert-butyl-4-(5-(1-(4-chlorophen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340821(4-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340803(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50260797(3-Biphenyl-4-yl-5-[1-(4-chloro-phenyl)-cyclobutyl]...)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse 11beta-HSD1 by SPA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340820(4-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340819(6-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340821(4-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340831(2-(3-chloro-4-(5-(1-(4-chlorophenyl)-3-fluorocyclo...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340792(CHEMBL1760683 | N-(4-(5-(1-(4-chlorophenyl)cyclobu...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340797(3-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  6nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340825(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340809(3-Adamantan-1-yl-5,6,7,8,9,10-hexahydro-[1,2,4]tri...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340822(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340796(CHEMBL1760687 | N-(4-(5-(1-(4-chlorophenyl)cyclobu...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340794(CHEMBL1760685 | N-(4-(5-(1-(4-chlorophenyl)cyclobu...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340817(6-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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