Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50022511
TargetSerine/threonine-protein kinase mTOR(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637407BDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 4nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652797BDBM50652797(CHEMBL5661831)
Affinity DataIC50: 7nMAssay Description:Competitive inhibition of mTORC2 immunoprecipitated from human HeLa cells using His-tagged 4E-BP1 as substrate incubated for 30 mins in presence of A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356877BDBM50356877(CHEMBL1614710)
Affinity DataIC50: 9nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652797BDBM50652797(CHEMBL5661831)
Affinity DataIC50: 11nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637407BDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 22nMAssay Description:Competitive inhibition of mTORC1 immunoprecipitated from human HeLa cells using His-tagged 4E-BP1 as substrate incubated for 30 mins in presence of A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652797BDBM50652797(CHEMBL5661831)
Affinity DataIC50: 29nMAssay Description:Competitive inhibition of mTORC1 immunoprecipitated from human HeLa cells using His-tagged 4E-BP1 as substrate incubated for 30 mins in presence of A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637407BDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 65nMAssay Description:Competitive inhibition of mTORC2 immunoprecipitated from human HeLa cells using His-tagged 4E-BP1 as substrate incubated for 30 mins in presence of A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50652797BDBM50652797(CHEMBL5661831)
Affinity DataIC50: 190nMAssay Description:Inhibition of PI3Kalpha (unknown origin) in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637407BDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 420nMAssay Description:Inhibition of PI3Kgamma (unknown origin) in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50652797BDBM50652797(CHEMBL5661831)
Affinity DataIC50: 460nMAssay Description:Inhibition of PI3Kgamma (unknown origin) in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637407BDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of DNA-PK activity (unknown origin) presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637407BDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652797BDBM50652797(CHEMBL5661831)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of DNA-PK activity (unknown origin) presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50652797BDBM50652797(CHEMBL5661831)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin) in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637407BDBM50637407(Osi 027 | Osi-027 | AEVI-006 | ASP 7486 | ASP-7486...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed