Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50033141
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340266(7-(2-(3-(4-chloro-2-methoxy-5-(trifluoromethyl)phe...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340264(7-(2-(3-(5-chloro-2-methoxy-4-methylphenyl)ureido)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340262(7-(2-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340273(CHEMBL1760633 | N-(6-(2-(3-(4-chloro-3-(trifluorom...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340259(7-(2-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340270(CHEMBL1760630 | N-(6-(2-(3-(2-methoxy-5-(trifluoro...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340285(CHEMBL1760736 | N-(6-(2-(3-(2-(2-aminoethoxy)-4-ch...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340265(7-(2-(3-(4-chloro-2-methoxy-5-methylphenyl)ureido)...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340277(CHEMBL1760637 | N-(6-(2-(3-(5-chloro-2-methoxy-4-m...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340258(CHEMBL1760619 | N-methyl-7-(2-(3-(4-methyl-3-(trif...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340288(CHEMBL1760617 | N-methyl-7-(2-(3-(3-(trifluorometh...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340281(CHEMBL1760641 | N-(6-(2-(3-(2-(2-(methylamino)etho...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340290(CHEMBL1760737 | N-(6-(2-(3-(2-(pyrrolidin-2-ylmeth...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340282(CHEMBL1760642 | N-(6-(2-(3-(4-chloro-2-(2-(methyla...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340260(7-(2-(3-(4-fluoro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340284(CHEMBL1760735 | N-(6-(2-(3-(2-(2-aminoethoxy)-5-(t...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340261(7-(2-(3-(2-fluoro-5-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340287(CHEMBL1760616 | N-methyl-7-(2-(3-(3-(trifluorometh...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340271(6-(2-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340278(CHEMBL1760638 | N-(6-(2-(3-(4-chloro-2-methoxy-5-m...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340267(7-(2-(3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-(t...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340268(6-(2-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340286(CHEMBL1760615 | N-methyl-7-(2-(3-(3-(trifluorometh...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340289(CHEMBL1760618 | N-methyl-7-(2-(3-(4-(trifluorometh...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340263(7-(2-(3-(2-(2-(dimethylamino)ethoxy)-5-(trifluorom...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340274(CHEMBL1760634 | N-(6-(2-(3-(3-(trifluoromethyl)phe...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340275(CHEMBL1760635 | N-(6-(2-(3-(3,4-dichlorophenyl)ure...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340280(CHEMBL1760640 | N-(6-(2-(3-(4-chloro-5-methyl-2-(2...)
Affinity DataIC50:  490nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340276(CHEMBL1760636 | N-(6-(2-(3-(3-chloro-4-methylpheny...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340283(CHEMBL1760643 | N-(6-(2-(3-(2-(2-aminoethoxy)-4-ch...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340279(CHEMBL1760639 | N-(6-(2-(3-(5-methyl-2-(2-(methyla...)
Affinity DataIC50:  580nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340272(CHEMBL1760632 | methyl 6-(2-(3-(4-chloro-3-(triflu...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340269(CHEMBL1760629 | methyl 6-(2-(3-(2-methoxy-5-(trifl...)
Affinity DataIC50:  810nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed