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Found 48 Enz. Inhib. hit(s) with all data for entry = 50033253
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50217448(CHEMBL242459 | US9029401, 1471 (t-AUCB) | trans-4-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342211(4-(5-Phenyl-3-{3-[3-(4-trifluoromethoxy-phenyl)-ur...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342208(4-{3-[3-(3-Cycloheptyl-ureido)-propyl]-5-phenyl-py...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342207(4-{3-[3-(3-Adamantan-1-yl-ureido)-propyl]-5-phenyl...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342209(4-(3-{3-[3-(4-Chloro-phenyl)-ureido]-propyl}-5-phe...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342206(4-{5-Phenyl-3-[3-(3-phenyl-ureido)-propyl]-pyrazol...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342210(4-(5-Phenyl-3-{3-[3-(4-trifluoromethyl-phenyl)-ure...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342193(1-Cycloheptyl-3-[1-(4-methanesulfonyl-phenyl)-5-ph...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342203(1-{3-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyr...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342202(4-(5-Phenyl-3-{3-[3-(3-trifluoromethyl-phenyl)-ure...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342195(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342204(4-(5-p-Tolyl-3-{3-[3-(3-trifluoromethyl-phenyl)-ur...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342192(1-Adamantan-1-yl-3-[1-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342201(4-(5-Phenyl-3-{2-[3-(3-trifluoromethyl-phenyl)-ure...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342199(1-[5-tert-Butyl-1-(4-methanesulfonyl-phenyl)-1H-py...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342194(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342197(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342198(4-{5-Phenyl-3-[3-(3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342200(4-{5-Phenyl-3-[3-(3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50:  88nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342196(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342202(4-(5-Phenyl-3-{3-[3-(3-trifluoromethyl-phenyl)-ure...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342211(4-(5-Phenyl-3-{3-[3-(4-trifluoromethoxy-phenyl)-ur...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342201(4-(5-Phenyl-3-{2-[3-(3-trifluoromethyl-phenyl)-ure...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342198(4-{5-Phenyl-3-[3-(3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342210(4-(5-Phenyl-3-{3-[3-(4-trifluoromethyl-phenyl)-ure...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342205(4-(3-{3-[3-(2,6-Diisopropyl-phenyl)-ureido]-propyl...)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342208(4-{3-[3-(3-Cycloheptyl-ureido)-propyl]-5-phenyl-py...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342200(4-{5-Phenyl-3-[3-(3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342197(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342204(4-(5-p-Tolyl-3-{3-[3-(3-trifluoromethyl-phenyl)-ur...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342203(1-{3-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyr...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342209(4-(3-{3-[3-(4-Chloro-phenyl)-ureido]-propyl}-5-phe...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342207(4-{3-[3-(3-Adamantan-1-yl-ureido)-propyl]-5-phenyl...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342195(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342194(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342206(4-{5-Phenyl-3-[3-(3-phenyl-ureido)-propyl]-pyrazol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342192(1-Adamantan-1-yl-3-[1-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342196(1-[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342199(1-[5-tert-Butyl-1-(4-methanesulfonyl-phenyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342193(1-Cycloheptyl-3-[1-(4-methanesulfonyl-phenyl)-5-ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50342205(4-(3-{3-[3-(2,6-Diisopropyl-phenyl)-ureido]-propyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50217448(CHEMBL242459 | US9029401, 1471 (t-AUCB) | trans-4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed