Compile Data Set for Download or QSAR
Report error Found 134 Enz. Inhib. hit(s) with all data for entry = 50033355
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343785BDBM50343785(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKd:  0.0300nMAssay Description:Binding affinity to wild type human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343785BDBM50343785(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKd:  0.0400nMAssay Description:Binding affinity to wild type human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119380BDBM50119380(CHEMBL540612 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161214BDBM50161214(PG-01037 | N-{4-[4-(2,3-Dichloro-phenyl)-piperazin...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343810BDBM50343810(benzo[b]thiophene-2-carboxylic acid{4-[4-(2,3-dich...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119384BDBM50119384(Benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-p...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343798BDBM50343798(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50071959BDBM50071959(9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343794BDBM50343794(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343796BDBM50343796(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343795BDBM50343795(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343793BDBM50343793(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343797BDBM50343797(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343785BDBM50343785(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [125I]-IABN from wild type human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343785BDBM50343785(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343799BDBM50343799(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343788BDBM50343788(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343791BDBM50343791(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343792BDBM50343792(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  9.5nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343786BDBM50343786(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  10.1nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11638BDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataIC50: 10.3nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as inhibition of quinpirole-induced mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343790BDBM50343790(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  13.9nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343796BDBM50343796(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as inhibition of quinpirole-induced mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343787BDBM50343787(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  20.5nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343789BDBM50343789(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  28.6nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119380BDBM50119380(CHEMBL540612 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  33.6nMAssay Description:Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343789BDBM50343789(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  37.9nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119384BDBM50119384(Benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-p...)
Affinity DataKi:  44.8nMAssay Description:Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343787BDBM50343787(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343810BDBM50343810(benzo[b]thiophene-2-carboxylic acid{4-[4-(2,3-dich...)
Affinity DataKi:  64.7nMAssay Description:Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11638BDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataIC50: 66.2nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as inhibition of quinpirole-induced mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343800BDBM50343800(N-(Benzo[b]thiophen-2-ylmethyl)-4-(4-(2-methoxyphe...)
Affinity DataKi:  67.9nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343800BDBM50343800(N-(Benzo[b]thiophen-2-ylmethyl)-4-(4-(2-methoxyphe...)
Affinity DataKi:  69.9nMAssay Description:Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343802BDBM50343802(N-((9H-Fluoren-2-yl)methyl)-4-(4-(2-methoxyphenyl)...)
Affinity DataKi:  71.5nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343787BDBM50343787(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataEC50:  71.6nMAssay Description:Agonist activity at 5HT1A receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343790BDBM50343790(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343804BDBM50343804(4-(4-(2-Methoxyphenyl)piperazin-1-yl)-N-(naphthale...)
Affinity DataKi:  80.8nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343795BDBM50343795(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataIC50: 83nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as inhibition of quinpirole-induced mitogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161214BDBM50161214(PG-01037 | N-{4-[4-(2,3-Dichloro-phenyl)-piperazin...)
Affinity DataKi:  93.3nMAssay Description:Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343788BDBM50343788(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  98nMAssay Description:Displacement of [125I]DOI from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343792BDBM50343792(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343801BDBM50343801(N-(Benzo[b]thiophen-2-ylmethyl)-4-(4-(2,3-dichloro...)
Affinity DataKi:  101nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343805BDBM50343805(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-N-(naphth...)
Affinity DataKi:  104nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50071959BDBM50071959(9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-...)
Affinity DataKi:  112nMAssay Description:Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343804BDBM50343804(4-(4-(2-Methoxyphenyl)piperazin-1-yl)-N-(naphthale...)
Affinity DataKi:  119nMAssay Description:Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343803BDBM50343803(N-((9H-Fluoren-2-yl)methyl)-4-(4-(2,3-dichlorophen...)
Affinity DataKi:  129nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343806BDBM50343806(4-(((9H-Fluoren-2-yl)methyl)amino)-1-(4-(2,3-dichl...)
Affinity DataKi:  134nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343789BDBM50343789(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataEC50:  134nMAssay Description:Agonist activity at 5HT1A receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343795BDBM50343795(N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)b...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343788BDBM50343788(N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-fluo...)
Affinity DataKi:  159nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
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