Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50033380
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344141((S)-6-(3-(3,5-difluorophenoxy)-5-(1-methoxypropan-...)
Affinity DataEC50:  90nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344160((S)-6-(3-(1-methoxypropan-2-yloxy)-5-(4-(methylsul...)
Affinity DataEC50:  60nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344142(6-(3-((S)-1-(4-fluorophenyl)propan-2-yloxy)-5-((S)...)
Affinity DataEC50:  40nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344143(6-(3-((S)-1-(2-methoxyphenyl)propan-2-yloxy)-5-((S...)
Affinity DataEC50:  70nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344144(6-(3-((S)-1-(3,5-difluorophenyl)propan-2-yloxy)-5-...)
Affinity DataEC50:  50nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344145(6-(3-((S)-1-(5-chlorofuran-2-yl)propan-2-yloxy)-5-...)
Affinity DataEC50:  30nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344146(6-(3-((S)-1-cyclopentylpropan-2-yloxy)-5-((S)-1-me...)
Affinity DataEC50:  90nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50183222((S)-6-(3-isopropoxy-5-(1-phenylpropan-2-yloxy)benz...)
Affinity DataEC50:  20nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344147((S)-6-(3-(1-methoxy-2-methylpropan-2-yloxy)-5-(1-p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344148((S)-6-(3-(1-phenylpropan-2-yloxy)-5-(tetrahydro-2H...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344149(6-(3-((S)-1-methoxypropan-2-yloxy)-5-((R)-2-phenyl...)
Affinity DataEC50:  70nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344150((S)-6-(3-(2,2-difluoro-2-phenylethoxy)-5-(1-methox...)
Affinity DataEC50:  30nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344151(6-(3-(2,3-dihydro-1H-inden-2-yloxy)-5-isopropoxybe...)
Affinity DataEC50:  100nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50183221((S)-6-(3-isopropoxy-5-(1-phenylethoxy)benzamido)ni...)
Affinity DataEC50:  150nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344152(6-(3-isopropoxy-5-phenoxybenzamido)nicotinic acid ...)
Affinity DataEC50:  210nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344153((S)-6-(3-(1-methoxypropan-2-yloxy)-5-phenoxybenzam...)
Affinity DataEC50:  160nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344154((S)-6-(3-(3-methoxyphenoxy)-5-(1-methoxypropan-2-y...)
Affinity DataEC50:  40nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344155((S)-6-(3-(4-methoxyphenoxy)-5-(1-methoxypropan-2-y...)
Affinity DataEC50:  60nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344156((S)-6-(3-(3-chlorophenoxy)-5-(1-methoxypropan-2-yl...)
Affinity DataEC50:  110nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344157((S)-6-(3-(4-chlorophenoxy)-5-(1-methoxypropan-2-yl...)
Affinity DataEC50:  100nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344158((S)-6-(3-(3-fluorophenoxy)-5-(1-methoxypropan-2-yl...)
Affinity DataEC50:  180nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50344159((S)-6-(3-(3-(dimethylamino)phenoxy)-5-(1-methoxypr...)
Affinity DataEC50:  400nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50320996(6-(3-((S)-1-methoxypropan-2-yloxy)-5-((S)-1-phenyl...)
Affinity DataEC50:  30nMAssay Description:Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed