Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50033413
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344869BDBM50344869(1'-pentyl-6H-spiro[benzofuro[6,5-d][1,3]dioxole-7,...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344821BDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344834BDBM50344834(3-(benzo[d][1,3]dioxol-5-yl)-1-(2-cyclopropylethyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344835BDBM50344835(3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-1-pentylind...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344859BDBM50344859(3-amino-3-(benzo[d][1,3]dioxol-5-yl)-1-pentylindol...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344836BDBM50344836(3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-1-(3-methyl...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344837BDBM50344837(3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-1-(4-methox...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344839BDBM50344839(3-(benzo[d][1,3]dioxol-5-yl)-1-((5-chlorothiophen-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344840BDBM50344840(3-(benzo[d][1,3]dioxol-5-yl)-1-(benzo[d][1,3]dioxo...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344838BDBM50344838(3-(benzo[d][1,3]dioxol-5-yl)-1-benzyl-3-hydroxyind...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344842BDBM50344842(3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-1-isopentyl...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344841BDBM50344841(3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-1-(4,4,4-tr...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344843BDBM50344843(3-(benzo[d][1,3]dioxol-5-yl)-1-(cyclopropylmethyl)...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344845BDBM50344845(3-(benzo[d][1,3]dioxol-5-yl)-1-(4-fluorobenzyl)-3-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344844BDBM50344844(3-(benzo[d][1,3]dioxol-5-yl)-1-hexyl-3-hydroxyindo...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344846BDBM50344846(3-(benzo[d][1,3]dioxol-5-yl)-1-(cyclohexylmethyl)-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344847BDBM50344847(3-(benzo[d][1,3]dioxol-5-yl)-1-(cyclobutylmethyl)-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344848BDBM50344848(3-(benzo[d][1,3]dioxol-5-yl)-1-(3,4-difluorobenzyl...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344818BDBM50344818(1-(4-chlorobenzyl)-3-hydroxy-3-(2-oxo-2-(thiophen-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344822BDBM50344822(3-(benzo[d][1,3]dioxol-5-yl)-1-(4-chlorobenzyl)-3-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344849BDBM50344849(3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-1-(4-(trifl...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344823BDBM50344823(1-(4-chlorobenzyl)-3-hydroxy-3-(6-methoxypyridin-3...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344817BDBM50344817(1-(4-chlorobenzyl)-3-(2-(furan-2-yl)-2-oxoethyl)-3...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344870BDBM50344870(1'-pentyl-6,7-dihydrospiro[indeno[5,6-d][1,3]dioxo...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344824BDBM50344824(1-(4-chlorobenzyl)-3-(2,3-dihydrobenzo[b][1,4]diox...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344853BDBM50344853(3-(benzo[d][1,3]dioxol-5-yl)-3-(hydroxymethyl)-1-p...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344858BDBM50344858(3-(benzo[d][1,3]dioxol-5-yl)-N-benzyl-2-oxo-1-pent...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344872BDBM50344872(1-pentyl-7'H-spiro[indoline-3,5'-isobenzofuro[5,6-...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344825BDBM50344825(1-(4-chlorobenzyl)-3-hydroxy-3-(3-methoxyphenyl)in...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344871BDBM50344871(1-pentyl-7',8'-dihydro-6'H-spiro[indoline-3,5'-nap...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344826BDBM50344826(1-(4-chlorobenzyl)-3-hydroxy-3-phenylindolin-2-one...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344855BDBM50344855(3-(benzo[d][1,3]dioxol-5-yl)-3-methyl-1-pentylindo...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344852BDBM50344852(3-(benzo[d][1,3]dioxol-5-yl)-1-pentylindolin-2-one...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344868BDBM50344868(1-pentyl-6'H-spiro[indoline-3,5'-naphtho[2,3-d][1,...)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344856BDBM50344856(methyl-3-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1-pentyl...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344850BDBM50344850(3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-1-(naphthal...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344827BDBM50344827(1-(4-chlorobenzyl)-3-(3,4-dihydro-2H-benzo[b][1,4]...)
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344867BDBM50344867(1'-pentylspiro[indeno[5,6-d][1,3]dioxole-5,3'-indo...)
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344828BDBM50344828(1-(4-chlorobenzyl)-3-(furan-3-yl)-3-hydroxyindolin...)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344832BDBM50344832(1-(4-chlorobenzyl)-3-(2,2-difluorobenzo[d][1,3]dio...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344854BDBM50344854(3-(benzo[d][1,3]dioxol-5-yl)-3-methoxy-1-pentylind...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344862BDBM50344862(2-(3-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1-pentylindo...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344861BDBM50344861(methyl-3-(3-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1-pen...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344864BDBM50344864(2-(3-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1-pentylindo...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344833BDBM50344833(3-(benzofuran-6-yl)-1-(4-chlorobenzyl)-3-hydroxyin...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344863BDBM50344863(3-(3-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1-pentylindo...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344866BDBM50344866(2-(3-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1-pentylindo...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344857BDBM50344857(3-(benzo[d][1,3]dioxol-5-yl)-N-methyl-2-oxo-1-pent...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344865BDBM50344865(2-(3-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1-pentylindo...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344851BDBM50344851(3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxyindolin-2-on...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
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