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Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50033705
TargetDNA topoisomerase 2-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50349933(CHEMBL1812144)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDNA topoisomerase 2-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50349934(CHEMBL1812139)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDNA topoisomerase 2-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50349932(CHEMBL1812137)
Affinity DataIC50:  4.88E+3nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDNA topoisomerase 2-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataIC50:  6.03E+4nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)