Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50033426
LigandChemical structure of BindingDB Monomer ID 31592BDBM31592(PF-2545920 | substituted pyrazole, 9 | US9138494, ...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50334653BDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345094BDBM50345094(2-methyl-5-((1-methyl-1H-benzo[d]imidazol-2-yl)met...)
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345091BDBM50345091(5-(imidazo[1,2-a]pyridin-2-ylmethylthio)-2-methyl-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319165BDBM50319165(2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...)
Affinity DataIC50: 32nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345103BDBM50345103(2-(9-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazol...)
Affinity DataIC50: 35nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345092BDBM50345092(5-(imidazo[1,2-a]pyrimidin-2-ylmethylthio)-2-methy...)
Affinity DataIC50: 55nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14768BDBM14768((R)-6,7-Dimethoxy-4-[3-(quinoxalin-2-yloxy)-pyrrol...)
Affinity DataIC50: 64nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345086BDBM50345086(5-((4-(4-methoxyphenyl)-1-methyl-1H-imidazol-2-yl)...)
Affinity DataIC50: 65nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345093BDBM50345093(2-((2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345089BDBM50345089(6-((2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...)
Affinity DataIC50: 120nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345102BDBM50345102(2-(9-chloro-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345087BDBM50345087(5-((4-(2-chlorophenyl)-1-methyl-1H-imidazol-2-yl)m...)
Affinity DataIC50: 150nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345090BDBM50345090(2-methyl-5-(quinolin-2-ylmethylthio)-[1,2,4]triazo...)
Affinity DataIC50: 160nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345110BDBM50345110(2-(2,10-dimethyl-[1,2,4]triazolo[1,5-c]quinazolin-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345088BDBM50345088(2-methyl-5-((1-methyl-4-phenyl-1H-imidazol-2-yl)me...)
Affinity DataIC50: 190nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14754BDBM14754(CHEMBL19224 | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50345101BDBM50345101(2-(9-methoxy-2-methyl-[1,2,4]triazolo[1,5-c]quinaz...)
Affinity DataIC50: 250nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345121BDBM50345121(2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylt...)
Affinity DataIC50: 310nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345112BDBM50345112(2-(8-fluoro-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 320nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345096BDBM50345096(2-methyl-5-(pyridin-4-ylmethylthio)-[1,2,4]triazol...)
Affinity DataIC50: 380nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345107BDBM50345107(2-(2-methyl-10-(trifluoromethyl)-[1,2,4]triazolo[1...)
Affinity DataIC50: 450nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345113BDBM50345113(2-(9-fluoro-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 460nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345109BDBM50345109(2-(2,9-dimethyl-[1,2,4]triazolo[1,5-c]quinazolin-5...)
Affinity DataIC50: 460nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345098BDBM50345098(2-(8,9-dimethoxy-2-methyl-[1,2,4]triazolo[1,5-c]qu...)
Affinity DataIC50: 790nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345116BDBM50345116(2-(2-((hydroxyimino)methyl)-[1,2,4]triazolo[1,5-c]...)
Affinity DataIC50: 960nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345095BDBM50345095(5-((1H-imidazol-2-yl)methylthio)-2-methyl-[1,2,4]t...)
Affinity DataIC50: 990nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345128BDBM50345128(5-(2-bromophenyl)-[1,2,4]triazolo[1,5-c]quinazolin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345106BDBM50345106(2-(10-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345108BDBM50345108(2-(2,8-dimethyl-[1,2,4]triazolo[1,5-c]quinazolin-5...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345122BDBM50345122(2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylt...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345118BDBM50345118(2-([1,2,4]triazolo[1,5-c]quinazolin-5-ylthio)aceto...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345120BDBM50345120(2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylt...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345111BDBM50345111(2-(7-fluoro-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345114BDBM50345114(2-(10-fluoro-2-methyl-[1,2,4]triazolo[1,5-c]quinaz...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345124BDBM50345124(2-methyl-5-(methylthio)-[1,2,4]triazolo[1,5-c]quin...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345104BDBM50345104(2-(2-methyl-8-(trifluoromethyl)-[1,2,4]triazolo[1,...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345103BDBM50345103(2-(9-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazol...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PDE4d6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345105BDBM50345105(2-(8-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazol...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345123BDBM50345123(5-(ethylthio)-2-methyl-[1,2,4]triazolo[1,5-c]quina...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345119BDBM50345119(4-(2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345126BDBM50345126((2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylsul...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345127BDBM50345127(5-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[1,5-c]quin...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345103BDBM50345103(2-(9-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazol...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of PDE5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345099BDBM50345099(2-(2-methyl-9-morpholino-[1,2,4]triazolo[1,5-c]qui...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345097BDBM50345097(1-(3,4-dichlorophenyl)-2-(2-methyl-[1,2,4]triazolo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345115BDBM50345115(2-(2-((methoxyimino)methyl)-[1,2,4]triazolo[1,5-c]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345100BDBM50345100(2-(2-methyl-9-phenyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345125BDBM50345125(2-methyl-[1,2,4]triazolo[1,5-c]quinazoline-5(6H)-t...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50345117BDBM50345117(2-(2-(hydroxymethyl)-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed