Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50022604
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant N-terminal GST-tagged FLT3 D835Y mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant N-terminal GST-tagged JAK2 V617F mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant N-terminal GST-tagged FLT3 (unknown origin) expressed in Bac-to-Bac baculovirus expression system incubated for 2 hrs using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant N-terminal GST-tagged JAK2 (unknown origin) expressed in Bac-to-Bac baculovirus expression system incubated for 2 hrs using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant N-terminal GST-tagged TYK2 (unknown origin) expressed in Bac-to-Bac baculovirus expression system incubated for 2 hrs using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant N-terminal GST-tagged JAK3 (unknown origin) expressed in Bac-to-Bac baculovirus expression system incubated for 2 hrs using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
S*BIO Pte Ltd

Curated by ChEMBL
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged JAK1 (unknown origin) expressed in Bac-to-Bac baculovirus expression system incubated for 2 hrs using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed