Compile Data Set for Download or QSAR
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Found 40 Enz. Inhib. hit(s) with all data for entry = 50004560
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50483940(CHEMBL1797097)
Affinity DataIC50:  63nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50483951(CHEMBL1797108)
Affinity DataIC50:  63nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484070(CHEMBL1806519)
Affinity DataIC50:  79nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484076(CHEMBL1808601)
Affinity DataIC50:  126nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50483940(CHEMBL1797097)
Affinity DataIC50:  200nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484083(CHEMBL1808599)
Affinity DataIC50:  200nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50483951(CHEMBL1797108)
Affinity DataIC50:  200nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484068(CHEMBL1808600)
Affinity DataIC50:  251nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484074(CHEMBL1808612)
Affinity DataIC50:  251nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484077(CHEMBL1808604)
Affinity DataIC50:  316nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484075(CHEMBL1808614)
Affinity DataIC50:  398nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484078(CHEMBL1808609)
Affinity DataIC50:  398nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484085(CHEMBL1808613)
Affinity DataIC50:  398nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484079(CHEMBL1808615)
Affinity DataIC50:  501nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484082(CHEMBL1808610)
Affinity DataIC50:  501nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484070(CHEMBL1806519)
Affinity DataIC50:  631nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484081(CHEMBL1808602)
Affinity DataIC50:  631nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484076(CHEMBL1808601)
Affinity DataIC50:  794nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484069(CHEMBL1808603)
Affinity DataIC50:  794nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484083(CHEMBL1808599)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484068(CHEMBL1808600)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484078(CHEMBL1808609)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484074(CHEMBL1808612)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484085(CHEMBL1808613)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484073(CHEMBL1808611)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484075(CHEMBL1808614)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484082(CHEMBL1808610)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484079(CHEMBL1808615)
Affinity DataIC50:  6.31E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484072(CHEMBL1808608)
Affinity DataIC50:  6.31E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484073(CHEMBL1808611)
Affinity DataIC50:  7.94E+3nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484071(CHEMBL1808607)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484081(CHEMBL1808602)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484072(CHEMBL1808608)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484071(CHEMBL1808607)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484077(CHEMBL1808604)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484084(CHEMBL1808606)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484069(CHEMBL1808603)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484084(CHEMBL1808606)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484080(CHEMBL1808605)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50484080(CHEMBL1808605)
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant Swedish variant of APP K595N/M596L assessed as reduction of amyloid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed