Compile Data Set for Download or QSAR
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Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50033738
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350510(CHEMBL1814815)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human full length SIRT2 using H2N-MPSD-AcK-TIGG-COOH as substrate assessed as enzymatic deacetylation product formation after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350510(CHEMBL1814815)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human SIRT3 (102-399) using H2N-KRLPKTRSG-AcK-VMRRLLRKII-COOH as substrate assessed as enzymatic deacetylation product formation after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350510(CHEMBL1814815)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human GST-tagged SIRT1 using H2NHK-AcK-LM-COOH as substrate assessed as enzymatic deacetylation product formation after 5 mins by HPLC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350509(CHEMBL1814814)
Affinity DataIC50:  5.72E+4nMAssay Description:Inhibition of human SIRT3 (102-399) using H2N-KRLPKTRSG-AcK-VMRRLLRKII-COOH as substrate assessed as enzymatic deacetylation product formation after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350509(CHEMBL1814814)
Affinity DataIC50:  8.95E+4nMAssay Description:Inhibition of human GST-tagged SIRT1 using H2NHK-AcK-LM-COOH as substrate assessed as enzymatic deacetylation product formation after 5 mins by HPLC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350509(CHEMBL1814814)
Affinity DataIC50:  1.59E+5nMAssay Description:Inhibition of human full length SIRT2 using H2N-MPSD-AcK-TIGG-COOH as substrate assessed as enzymatic deacetylation product formation after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350511(CHEMBL1814816)
Affinity DataIC50:  1.90E+5nMAssay Description:Inhibition of human full length SIRT2 using H2N-MPSD-AcK-TIGG-COOH as substrate assessed as enzymatic deacetylation product formation after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350511(CHEMBL1814816)
Affinity DataIC50:  2.14E+5nMAssay Description:Inhibition of human SIRT3 (102-399) using H2N-KRLPKTRSG-AcK-VMRRLLRKII-COOH as substrate assessed as enzymatic deacetylation product formation after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350511(CHEMBL1814816)
Affinity DataIC50:  2.90E+5nMAssay Description:Inhibition of human GST-tagged SIRT1 using H2NHK-AcK-LM-COOH as substrate assessed as enzymatic deacetylation product formation after 5 mins by HPLC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed